A novel approach: targeting virulence factors of Candida albicans with essential oil components

AMA Shaban, H Darmani - Journal of Applied Microbiology, 2024 - academic.oup.com
Aims Focusing on phytochemicals to target the virulence factors of Candida albicans is a
promising avenue for novel antifungal compounds. Given the limited prior research on …

Novel essential oils target the virulence factors of Candida albicans

H Darmani, AT Elwan… - Australian Journal of …, 2022 - search.informit.org
Candida albicans (C. albicans) biofilm-related diseases remain a major challenge for
clinicians due to the formidable and increasing resistance to commonly used antifungal …

The Effects of Mentha × piperita Essential Oil on C. albicans Growth, Transition, Biofilm Formation, and the Expression of Secreted Aspartyl Proteinases Genes

C Benzaid, A Belmadani, R Djeribi, M Rouabhia - Antibiotics, 2019 - mdpi.com
The rise in resistance and changes in the spectrum of Candida infections have generated
enormous interest in developing new antifungal drugs using natural molecules such as plant …

Cinnamon Leaf and Clove Essential Oils Are Potent Inhibitors of Candida albicans Virulence Traits

Z Shahina, A Molaeitabari, T Sultana, TES Dahms - Microorganisms, 2022 - mdpi.com
Plant-based essential oils are promising anti-virulence agents against the multidrug-
resistant opportunistic pathogen Candida albicans. Gas chromatography–mass …

Candida albicans Reactive Oxygen Species (ROS)-Dependent Lethality and ROS-Independent Hyphal and Biofilm Inhibition by Eugenol and Citral

Z Shahina, E Ndlovu, O Persaud, T Sultana… - Microbiology …, 2022 - Am Soc Microbiol
Candida albicans is part of the normal human flora but is most frequently isolated as the
causative opportunistic pathogen of candidiasis. Plant-based essential oils and their …

Back to Nature: Combating Candida albicans Biofilm, Phospholipase and Hemolysin Using Plant Essential Oils

AM El-Baz, RA Mosbah, RM Goda, B Mansour… - Antibiotics, 2021 - mdpi.com
Candida albicans is the causative agent of fatal systemic candidiasis. Due to limitations of
antifungals, new drugs are needed. The anti-virulence effect of plant essential oils (EOs) …

Origanum vulgare L. essential oil inhibits virulence patterns of Candida spp. and potentiates the effects of fluconazole and nystatin in vitro

C Cid-Chevecich, A Müller-Sepúlveda, JA Jara… - … Medicine and Therapies, 2022 - Springer
Background Recurrence and resistance of Candida spp. infections is associated with the
ability of these microorganisms to present several virulence patterns such as …

Essential oils as promising treatments for treating Candida albicans infections: research progress, mechanisms, and clinical applications

G Hou, T Hunag - Frontiers in Pharmacology, 2024 - frontiersin.org
Candida albicans:(C. alb icans) is a prevalent opportunistic pathogen that can cause severe
mucosal and systemic fungal infections, leading to high morbidity and mortality rates …

Antifungal Activity of Commercial Essential Oils and Biocides against Candida Albicans

E Serra, LA Hidalgo-Bastida, J Verran, D Williams… - Pathogens, 2018 - mdpi.com
Management of oral candidosis, most frequently caused by Candida albicans, is limited due
to the relatively low number of antifungal drugs and the emergence of antifungal tolerance …

Antibiofilm and Antihyphal Activities of Cedar Leaf Essential Oil, Camphor, and Fenchone Derivatives against Candida albicans

RK Manoharan, JH Lee, J Lee - Frontiers in microbiology, 2017 - frontiersin.org
Candida albicans can form biofilms composed of yeast, hyphal, and pseudohyphal
elements, and C. albicans cells in the hyphal stage could be a virulence factor. The present …