Subtle variation in sepsis-III definitions markedly influences predictive performance within and across methods

SN Cohen, J Foster, P Foster, H Lou, T Lyons… - Scientific Reports, 2024 - nature.com
Early detection of sepsis is key to ensure timely clinical intervention. Since very few end-to-
end pipelines are publicly available, fair comparisons between methodologies are difficult if …

Effect of a sepsis prediction algorithm on patient mortality, length of stay, and readmission

H Burdick, E Pino, D Gabel-Comeau, A McCoy, C Gu… - bioRxiv, 2018 - biorxiv.org
Objective To validate performance of a machine learning algorithm for severe sepsis
determination up to 48 hours before onset, and to evaluate the effect of the algorithm on in …

Developing an interpretable machine learning model to predict in-hospital mortality in sepsis patients: a retrospective temporal validation study

S Li, R Dou, X Song, KY Lui, J Xu, Z Guo, X Hu… - Journal of Clinical …, 2023 - mdpi.com
Background: Risk stratification plays an essential role in the decision making for sepsis
management, as existing approaches can hardly satisfy the need to assess this …

[HTML][HTML] Early prediction of sepsis from clinical data: the PhysioNet/Computing in Cardiology Challenge 2019

MA Reyna, CS Josef, R Jeter… - Critical care …, 2020 - journals.lww.com
Objectives: Sepsis is a major public health concern with significant morbidity, mortality, and
healthcare expenses. Early detection and antibiotic treatment of sepsis improve outcomes …

Machine learning for the prediction of sepsis: a systematic review and meta-analysis of diagnostic test accuracy

LM Fleuren, TLT Klausch, CL Zwager… - Intensive care …, 2020 - Springer
Purpose Early clinical recognition of sepsis can be challenging. With the advancement of
machine learning, promising real-time models to predict sepsis have emerged. We …

Evaluating a sepsis prediction machine learning algorithm in the emergency department and intensive care unit: a before and after comparative study

H Burdick, E Pino, D Gabel-Comeau, C Gu, H Huang… - BioRxiv, 2017 - biorxiv.org
Introduction Sepsis is a major health crisis in US hospitals, and several clinical identification
systems have been designed to help care providers with early diagnosis of sepsis. However …

Evaluation of sepsis prediction models before onset of treatment

F Kamran, D Tjandra, A Heiler, J Virzi, K Singh, JE King… - NEJM AI, 2024 - ai.nejm.org
Background Timely interventions, such as antibiotics and intravenous fluids, have been
associated with reduced mortality in patients with sepsis. Artificial intelligence (AI) models …

Prediction of Sepsis Mortality in ICU Patients Using Machine Learning Methods

J Gao, Y Lu, N Ashrafi, I Domingo, K Alaei, M Pishgar - medRxiv, 2024 - medrxiv.org
Problem Sepsis, a life-threatening condition, accounts for the deaths of millions of people
worldwide. Accurate prediction of sepsis outcomes is crucial for effective treatment and …

Multicentre validation of a sepsis prediction algorithm using only vital sign data in the emergency department, general ward and ICU

Q Mao, M Jay, JL Hoffman, J Calvert, C Barton… - BMJ open, 2018 - bmjopen.bmj.com
Objectives We validate a machine learning-based sepsis-prediction algorithm (InSight) for
the detection and prediction of three sepsis-related gold standards, using only six vital signs …

Development and validation of an interpretable model for predicting sepsis mortality across care settings

YS Lee, S Han, YE Lee, J Cho, YK Choi, SY Yoon… - Scientific Reports, 2024 - nature.com
There are numerous prognostic predictive models for evaluating mortality risk, but current
scoring models might not fully cater to sepsis patients' needs. This study developed and …