[HTML][HTML] Microbiome preterm birth DREAM challenge: crowdsourcing machine learning approaches to advance preterm birth research

JL Golob, TT Oskotsky, AS Tang, A Roldan… - Cell Reports …, 2024 - cell.com
Every year, 11% of infants are born preterm with significant health consequences, with the
vaginal microbiome a risk factor for preterm birth. We crowdsource models to predict (1) …

Maternal microbiomes in preterm birth: recent progress and analytical pipelines

LA Parnell, CM Briggs, IU Mysorekar - Seminars in perinatology, 2017 - Elsevier
Worldwide, 10% of babies are born preterm, defined as birth before 37 weeks' gestation. We
have had little success in developing strategies to prevent preterm births, the majority of …

Microdiversity of the vaginal microbiome is associated with preterm birth

J Liao, L Shenhav, JA Urban, M Serrano, B Zhu… - Nature …, 2023 - nature.com
Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality. The vaginal
microbiome has been associated with PTB, yet the mechanisms underlying this association …

Microbiome in parturition and preterm birth

IU Mysorekar, B Cao - Seminars in reproductive medicine, 2014 - thieme-connect.com
Preterm parturition is a one of the most significant global maternal-child health problem. In
recent years, there has been an explosion in reports on a role for microbiomes (ie, a …

Metagenomic analysis of mother-infant gut microbiome reveals global distinct and shared microbial signatures

S Wang, S Zeng, M Egan, P Cherry, C Strain… - Gut …, 2021 - Taylor & Francis
Emerging evidence indicates maternal microbiota as one major reservoir for pioneering
microbes in infants. However, the global distinct and identical features of mother–infant gut …

Preterm birth is correlated with increased oral originated microbiome in the gut

C Yin, J Chen, X Wu, Y Liu, Q He, Y Cao… - Frontiers in Cellular …, 2021 - frontiersin.org
Background Preterm birth is one of the leading causes of perinatal morbidity and mortality.
Gut microbiome dysbiosis is closely related to adverse pregnancy outcomes. However, the …

Maternal microbiome–a pathway to preterm birth

AE Vinturache, C Gyamfi-Bannerman, J Hwang… - Seminars in Fetal and …, 2016 - Elsevier
Despite great medical advances in preventing maternal and infant mortality in the past
century, one issue remains unresolved: why do so many women give birth prematurely? A …

[HTML][HTML] Diversity scaling of human vaginal microbial communities

W Li, MZS Sam - Zoological Research, 2019 - ncbi.nlm.nih.gov
The composition and diversity of the human vaginal microbial community have been
investigated intensively due to the diversity-stability relationship (DSR)-based hypothesis for …

The microbiome in preterm birth

DM Chu, M Seferovic, RM Pace, KM Aagaard - Best practice & research …, 2018 - Elsevier
The microbiome is thought to play a role in the maintenance of a healthy pregnancy and
thus may either contribute to or protect from preterm birth. Study of the human microbiome …

The placenta harbors a unique microbiome

K Aagaard, J Ma, KM Antony, R Ganu… - Science translational …, 2014 - science.org
Humans and their microbiomes have coevolved as a physiologic community composed of
distinct body site niches with metabolic and antigenic diversity. The placental microbiome …