From antigen uptake to immune modulation: the multifaceted potential of peptide nanofibers as vaccine nanocarriers
Spanning from the mitigation of pathogenic diseases via protective immunity to the provision
of therapeutic solutions for other debilitating ailments, immune-based interventions have …
of therapeutic solutions for other debilitating ailments, immune-based interventions have …
Comparative study of α-helical and β-sheet self-assembled peptide nanofiber vaccine platforms: influence of integrated T-cell epitopes
Several different self-assembling peptide systems that form nanofibers have been
investigated as vaccine platforms, but design principles for adjusting the character of the …
investigated as vaccine platforms, but design principles for adjusting the character of the …
Antigenic peptide nanofibers elicit adjuvant-free CD8+ T cell responses
CB Chesson, EJ Huelsmann, AT Lacek, FJ Kohlhapp… - Vaccine, 2014 - Elsevier
Vaccines that elicit robust CD8+ T cell responses are desirable for protection against
infectious diseases and cancers. However, most vaccine adjuvants fail to elicit robust CD8+ …
infectious diseases and cancers. However, most vaccine adjuvants fail to elicit robust CD8+ …
Effect of the hydrophilic-hydrophobic balance of antigen-loaded peptide nanofibers on their cellular uptake, cellular toxicity, and immune stimulatory properties
T Waku, S Nishigaki, Y Kitagawa, S Koeda… - International Journal of …, 2019 - mdpi.com
Recently, nanofibers (NFs) formed from antigenic peptides conjugated to β-sheet-forming
peptides have attracted much attention as a new generation of vaccines. However, studies …
peptides have attracted much attention as a new generation of vaccines. However, studies …
Controlled Lengthwise Assembly of Helical Peptide Nanofibers to Modulate CD8+ T‐Cell Responses
Peptide nanofibers are useful for many biological applications, including immunotherapy,
tissue engineering, and drug delivery. The robust lengthwise assembly of these peptides …
tissue engineering, and drug delivery. The robust lengthwise assembly of these peptides …
A modular antigen presenting peptide/oligonucleotide nanostructure platform for inducing potent immune response
The design and development of vaccines, which can induce cellular immunity, particularly
CD8+ T cells hold great importance since these cells play crucial roles against cancers and …
CD8+ T cells hold great importance since these cells play crucial roles against cancers and …
[HTML][HTML] Tuning surface charges of peptide nanofibers for induction of antigen-specific immune tolerance: an introductory study
Induction of antigen-specific immune tolerance has emerged as the next frontier in treating
autoimmune disorders, including atherosclerosis and graft-vs-host reactions during …
autoimmune disorders, including atherosclerosis and graft-vs-host reactions during …
Harnessing self-assembling peptide nanofibers to prime robust tumor-specific CD8 T cell responses in mice
Induction of tumor-specific CD8+ T cell responses is known as a major challenge for cancer
vaccine development; here we presented a strategy to improve peptide nanofibers-mounted …
vaccine development; here we presented a strategy to improve peptide nanofibers-mounted …
[PDF][PDF] Recent advances in peptide-based nanovaccines for re-emerging and emerging infectious diseases
F Orosco - J. Adv. Biotechnol. Exp. Ther, 2024 - researchgate.net
Peptide-based nanovaccines have emerged as promising strategies for combating
reemerging and emerging infectious diseases. They exhibit excellent immunogenicity and …
reemerging and emerging infectious diseases. They exhibit excellent immunogenicity and …
Rational design of charged peptides that self-assemble into robust nanofibers as immune-functional scaffolds
Self-assembling peptides programed by sequence design to form predefined nanostructures
are useful for a variety of biomedical applications. However, assemblies of classic ionic self …
are useful for a variety of biomedical applications. However, assemblies of classic ionic self …
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