Transdermal administration of farnesol-ethosomes enhances the treatment of cutaneous candidiasis induced by Candida albicans in mice

T Shen, B Tian, W Liu, X Yang, Q Sheng… - Microbiology …, 2024 - Am Soc Microbiol
Cutaneous candidiasis, caused by Candida albicans, is a severe and frustrating condition,
and finding effective treatments can be challenging. Therefore, the development of farnesol …

Nanoethosomal formulation for skin targeting of amphotericin B: an in vitro and in vivo assessment

L Kaur, SK Jain, RK Manhas… - Journal of liposome …, 2015 - Taylor & Francis
The present study is envisaged to develop nanoethosomal formulation for enhanced topical
delivery of amphotericin B (AmB) for the treatment of cutaneous fungal infections. AmB …

Development, characterization and in vitro–in vivo evaluation of Farnesol loaded niosomal gel for applications in oral candidiasis treatment

T Barot, D Rawtani, P Kulkarni - Heliyon, 2021 - cell.com
Objectives The aim of the study was to formulate and characterize the farnesol loaded
niosomes comprising gel formulation and perform their in vitro–in vivo evaluation for …

Ethosomes: a novel delivery system for antifungal drugs in the treatment of topical fungal diseases

MK Bhalaria, S Naik, AN Misra - 2009 - nopr.niscpr.res.in
Aim of this work was to prepare and characterize fluconazole (FLZ) encapsulated
ethosomes, incorporate it in suitable dermatological base, and asses its comparative clinical …

Soft Malleable Vesicles: versatile carriers for efficient topical delivery of fungal therapeutics

P Gupta, AK Jha, M Prasad, P Kushwaha - Drug Research, 2021 - thieme-connect.com
Fungal infections have become a subject of great concern and the incidence of fungal
infections is increasing, presenting an enormous challenge to healthcare professionals …

Utilization of PEGylated cerosomes for effective topical delivery of fenticonazole nitrate: in-vitro characterization, statistical optimization, and in-vivo assessment

R Albash, C Yousry, AM Al-Mahallawi… - Drug Delivery, 2021 - Taylor & Francis
In this investigation, we focused on ceramide IIIB, a skin component whose depletion tends
to augment multiple skin disorders and fungal infections. Ceramide IIIB was included into …

Design and synthesis of mucoadhesive nanogel containing farnesol: investigation of the effect on HWP1, SAP6 and Rim101 genes expression of Candida albicans in …

F Nikoomanesh, S Roudbarmohammadi… - Artificial cells …, 2019 - Taylor & Francis
The evolution of drug resistance of Candida species to conventional antifungal agents has
been a major medical challenge worldwide; attempt to use the potential antifungal agents …

In Vivo Evaluation of Miconazole-Nitrate-Loaded Transethosomal Gel Using a Rat Model Infected with Candida albicans

Z Asghar, T Jamshaid, U Jamshaid, A Madni, N Akhtar… - Pharmaceuticals, 2024 - mdpi.com
Miconazole nitrate (MCNR), an antifungal drug, is used to treat superficial infections. The
objective of the current study was to assess the antifungal effectiveness of MCNR-loaded …

In vitro synergistic effect of farnesol and human gingival cells against Candida albicans

S Saidi, C Luitaud, M Rouabhia - Yeast, 2006 - Wiley Online Library
Farnesol prevents the germination of yeast cells into mycelia, a fact that may be useful in
eliminating C. albicans pathogenicity. Given the clinical potential of farnesol, its impact on C …

Oleic acid vesicles: a new approach for topical delivery of antifungal agent

S Verma, A Bhardwaj, M Vij, P Bajpai… - Artificial cells …, 2014 - Taylor & Francis
The occurrence of topical fungal infections is increasing nowadays. Cutaneous fungal
infections like cutaneous candidiasis are more prominent in patients associated with AIDS …