Immune responses to human fungal pathogens and therapeutic prospects
MS Lionakis, RA Drummond, TM Hohl - Nature Reviews Immunology, 2023 - nature.com
Pathogenic fungi have emerged as significant causes of infectious morbidity and death in
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …
[HTML][HTML] Antifungal drug-resistance mechanisms in Candida biofilms
Highlights•Few classes of antifungal drugs currently exist to treat fungal infections.•Infections
caused by Candida biofilms can be resistant to known antifungal drugs.•Growth in the …
caused by Candida biofilms can be resistant to known antifungal drugs.•Growth in the …
Invasive candidiasis
Invasive candidiasis is an important fungal disease caused by Candida albicans and,
increasingly, non-albicans Candida pathogens. Invasive Candida infections originate most …
increasingly, non-albicans Candida pathogens. Invasive Candida infections originate most …
DSF-family quorum sensing signal-mediated intraspecies, interspecies, and inter-kingdom communication
While most bacteria are unicellular microbes they communicate with each other and with
their environments to adapt their behaviors. Quorum sensing (QS) is one of the best-studied …
their environments to adapt their behaviors. Quorum sensing (QS) is one of the best-studied …
Virulence Factors of Candida spp. and Host Immune Response Important in the Pathogenesis of Vulvovaginal Candidiasis
P Czechowicz, J Nowicka, G Gościniak - International journal of molecular …, 2022 - mdpi.com
Vulvovaginal candidiasis (VVC) is one of the most common types of vaginal infections in
women around the world and is often underestimated by both patients and doctors …
women around the world and is often underestimated by both patients and doctors …
C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection
Systemic candidiasis is a common, high-mortality, nosocomial fungal infection.
Unexpectedly, it has emerged as a complication of anti-complement C5-targeted …
Unexpectedly, it has emerged as a complication of anti-complement C5-targeted …
The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates filamentation, biofilm formation, and …
VE Glazier, J Kramara, T Ollinger, NV Solis… - MBio, 2023 - Am Soc Microbiol
Candida albicans is a diploid human fungal pathogen that displays significant genomic and
phenotypic heterogeneity over a range of virulence traits and in the context of a variety of …
phenotypic heterogeneity over a range of virulence traits and in the context of a variety of …
The Interplay between Candida albicans, Vaginal Mucosa, Host Immunity and Resident Microbiota in Health and Disease: An Overview and Future Perspectives
Vulvovaginal candidiasis (VVC), which is primarily caused by Candida albicans, is an
infection that affects up to 75% of all reproductive-age women worldwide. Recurrent VVC …
infection that affects up to 75% of all reproductive-age women worldwide. Recurrent VVC …
We need to talk about Candida tropicalis: Virulence factors and survival mechanisms
MM Dos Santos, K Ishida - Medical mycology, 2023 - academic.oup.com
Candida tropicalis is a notable species of the Candida genus representing an impressive
epidemiology in tropical regions, especially in South America and Asia, where India already …
epidemiology in tropical regions, especially in South America and Asia, where India already …
Intravital imaging-based genetic screen reveals the transcriptional network governing Candida albicans filamentation during mammalian infection
Candida albicans is one of the most common human fungal pathogens. C. albicans
pathogenesis is tightly linked to its ability to under a morphogenetic transition from typically …
pathogenesis is tightly linked to its ability to under a morphogenetic transition from typically …