Research progress in the molecular mechanism of ferroptosis in Parkinson's disease and regulation by natural plant products

K Yang, L Zeng, J Zeng, Y Deng, S Wang, H Xu… - Ageing Research …, 2023 - Elsevier
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder of the
central nervous system after Alzheimer's disease. The current understanding of PD focuses …

[HTML][HTML] Natural compounds efficacy in complicated diabetes: A new twist impacting ferroptosis

T Bao, X Zhang, W Xie, Y Wang, X Li, C Tang… - Biomedicine & …, 2023 - Elsevier
Ferroptosis, as a way of cell death, participates in the body's normal physiological and
pathological regulation. Recent studies have shown that ferroptosis may damage glucose …

Paeoniflorin confers ferroptosis resistance by regulating the gut microbiota and its metabolites in diabetic cardiomyopathy

H Wu, P Zhang, J Zhou, S Hu, J Hao… - … of Physiology-Cell …, 2024 - journals.physiology.org
Diabetic cardiomyopathy (DCM) is closely related to ferroptosis, a new type of cell death that
mainly manifests as intracellular iron accumulation and lipid peroxidation. Paeoniflorin (PA) …

Paeoniflorin attenuates particulate matter-induced acute lung injury by inhibiting oxidative stress and NLRP3 inflammasome-mediated pyroptosis through activation of …

W Zhou, H Zuo, Y Qian, W Miao, C Chen - Chemico-Biological Interactions, 2024 - Elsevier
Particulate matter (PM), the main component of air pollutants, emerges as a research
hotspot, especially in the area of respiratory diseases. Paeoniflorin (PAE), known as anti …

The natural polyphenol fisetin in atherosclerosis prevention: a mechanistic review

W Yu, Y Zhao, I Ilyas, L Wang… - Journal of Pharmacy …, 2024 - academic.oup.com
The incidence and mortality rate of atherosclerotic cardiovascular disease (ASCVD) is
increasing yearly worldwide. Recently, a growing body of evidence has unveiled the anti …

Promoting reverse cholesterol transport contributes to the amelioration of atherosclerosis by paeoniflorin

RM Wu, CY Wang, J Wang, X Le Xu - European Journal of Pharmacology, 2023 - Elsevier
Reverse cholesterol transport (RCT) offers a practical approach to mitigating
atherosclerosis. Paeoniflorin, a monoterpenoid glycoside found in plants of the …

Role of the HIF-1α/BNIP3 Signaling Pathway in Recurrent Hepatocellular Carcinoma and the Mechanism of Traditional Chinese Medicine

S Liu, L Kang, Y Song, M Miao - Journal of Hepatocellular …, 2023 - Taylor & Francis
Recurrence of hepatocellular carcinoma (HCC) negatively affects the quality of life of
patients and leads to death. Studies have shown that recurrent hepatocellular carcinoma …

Evaluation of drug interactions of Saposhnikoviae Radix and its major components with astragaloside IV and paeoniflorin using in vitro and in vivo experiments

Q Wang, S Liu, D Yu, P Chen, Y Wang, F Lu… - … of Chromatography A, 2024 - Elsevier
Saposhnikoviae Radix (SR) may enhance the pharmacodynamics of Huangqi Chifeng Tang
(HQCFT) in the treatment of cerebral infarction according to our previous research, but the …