Macrophage polarization and its role in the pathogenesis of acute lung injury/acute respiratory distress syndrome

X Chen, J Tang, W Shuai, J Meng, J Feng, Z Han - Inflammation Research, 2020 - Springer
Purpose Macrophages are highly plastic cells. Under different stimuli, macrophages can be
polarized into several different subsets. Two main macrophage subsets have been …

Rutin (Bioflavonoid) as cell signaling pathway modulator: Prospects in treatment and chemoprevention

P Pandey, F Khan, HA Qari, M Oves - Pharmaceuticals, 2021 - mdpi.com
Cancer is a complex ailment orchestrated by numerous intrinsic and extrinsic pathways.
Recent research has displayed a deep interest in developing plant-based cancer …

Xuanfei Baidu Decoction reduces acute lung injury by regulating infiltration of neutrophils and macrophages via PD-1/IL17A pathway

Y Wang, X Wang, Y Li, Z Xue, R Shao, L Li, Y Zhu… - Pharmacological …, 2022 - Elsevier
The pathogenic hyper-inflammatory response has been revealed as the major cause of the
severity and death of the Corona Virus Disease 2019 (COVID-19). Xuanfei Baidu Decoction …

The phase changes of M1/M2 phenotype of microglia/macrophage following oxygen-induced retinopathy in mice

J Li, S Yu, X Lu, K Cui, X Tang, Y Xu, X Liang - Inflammation Research, 2021 - Springer
Objective Microglia/macrophage activation is previously reported to be involved in various
ocular diseases. However, the separate role of M1/M2 phenotype microglia/macrophage in …

Extracellular vesicle/macrophage axis: potential targets for inflammatory disease intervention

D Tang, F Cao, C Yan, K Fang, J Ma, L Gao… - Frontiers in …, 2022 - frontiersin.org
Extracellular vesicles (EVs) can regulate the polarization of macrophages in a variety of
inflammatory diseases by mediating intercellular signal transduction and affecting the …

The Regulatory Role of α‐Ketoglutarate Metabolism in Macrophages

S Liu, J Yang, Z Wu - Mediators of inflammation, 2021 - Wiley Online Library
Macrophages are multifunctional immune cells whose functions depend on polarizable
phenotypes and the microenvironment. Macrophages have two phenotypes, including the …

Mesenchymal stem cells promote polarization of M2 macrophages in mice with acute-on-chronic liver failure via Mertk/JAK1/STAT6 signaling

ZH Li, JF Chen, J Zhang, ZY Lei, LL Wu, SB Meng… - Stem Cells, 2023 - academic.oup.com
Acute-on-chronic liver failure (ACLF) is a severe disease with a high mortality. Macrophage-
related inflammation plays a crucial role in ACLF development. Mesenchymal stem cells …

Recent advancement on development of drug-induced macrophage polarization in control of human diseases

L Wang, Q Lu, W Gao, S Yu - Life sciences, 2021 - Elsevier
Macrophages, an important part of human immune system, possess a high plasticity and
heterogeneity (macrophage polarization) as classically activated macrophages (M1) and …

Artificially induced in situ macrophage polarization: An emerging cellular therapy for immuno-inflammatory diseases

O Chaterjee, D Sur - European Journal of Pharmacology, 2023 - Elsevier
Macrophages are the mature form of monocytes that have high plasticity and can shift from
one phenotype to another by the process of macrophage polarization. Macrophage has …

[HTML][HTML] Roles of immune dysregulation in MASLD

T Dong, J Li, Y Liu, S Zhou, X Wei, H Hua… - Biomedicine & …, 2024 - Elsevier
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common
chronic liver disease worldwide. Its occurrence and progression involve the process from …