The adaptive immune response mediated by T cells is critical for control of Mycobacterium
tuberculosis (M. tuberculosis) infection in humans. However, the M. tuberculosis antigens …

The outcome of Mycobacterium tuberculosis (Mtb) infection ranges from a complete
pathogen clearance through asymptomatic latent infection (LTBI) to active tuberculosis (TB) …

With 1.4 million deaths and 8.7 million new cases in 2011, tuberculosis (TB) remains a
global health care problem and together with HIV and Malaria represents one of the three …

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), infects one third
of the world's population. Among these infections, clinical isolates belonging to the W …

В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

Rationale: A hallmark of pulmonary tuberculosis (TB) is the formation of granulomas.
However, the immune factors that drive the formation of a protective granuloma during latent …

Respiratory infections and diseases are among the leading causes of death worldwide, and
effective treatments probably require manipulating the inflammatory response to pathogenic …

Mycobacterium tuberculosis complex causes tuberculosis (TB), one of the top 10 causes of
death worldwide. TB results in more fatalities than multi-drug resistant (MDR) HIV strain …

We performed a quantitative analysis of the HLA restriction, antigen and epitope specificity
of human pathogen specific responses in healthy individuals infected with M. tuberculosis …

Tuberculosis (TB) is the leading killer among all infectious diseases worldwide despite
extensive use of the Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine. A safer …