Th17 cells in periodontitis and its regulation by A20

N Huang, H Dong, Y Luo, B Shao - Frontiers in immunology, 2021 - frontiersin.org
Periodontitis is a prevalent chronic disease that results in loss of periodontal ligament and
bone resorption. Triggered by pathogens and prolonged inflammation, periodontitis is …

The regulative effect and repercussion of probiotics and prebiotics on osteoporosis: involvement of brain-gut-bone axis

YW Zhang, MM Cao, YJ Li, GC Dai, PP Lu… - Critical reviews in …, 2023 - Taylor & Francis
Osteoporosis (OP) is a systemic disease characterized by decreased bone mass and
degeneration of bone microstructure. In recent years, more and more researches have …

Osteoimmunology: The correlation between osteoclasts and the Th17/Treg balance in osteoporosis

F Huang, P Wong, J Li, Z Lv, L Xu… - Journal of Cellular …, 2022 - Wiley Online Library
Osteoporosis is a bone disease that is caused by disorder of the skeletal microenvironment,
and it characterized by a high disability rate and the occurrence of low energy fractures …

The Th17/Treg cell balance: crosstalk among the immune system, bone and microbes in periodontitis

J Deng, C Lu, Q Zhao, K Chen, S Ma… - Journal of periodontal …, 2022 - Wiley Online Library
Periodontopathic bacteria constantly stimulate the host, which causes an immune response,
leading to host‐induced periodontal tissue damage. The complex interaction and imbalance …

Natural aporphine alkaloids with potential to impact metabolic syndrome

FX Wang, N Zhu, F Zhou, DX Lin - Molecules, 2021 - mdpi.com
The incidence and prevalence of metabolic syndrome has steadily increased worldwide. As
a major risk factor for various diseases, metabolic syndrome has come into focus in recent …

Age-and sex-related differences of periodontal bone resorption, cognitive function, and immune state in APP/PS1 murine model of Alzheimer's disease

H Chen, Y Liao, X Zhang, H Shen, D Shang… - Journal of …, 2023 - Springer
Background The existence of an interconnected mechanism between cognitive disorders
and periodontitis has been confirmed by mounting evidence. However, the role of age or sex …

Immunotherapy with regulatory T and B cells in periodontitis

J Zou, Z Zeng, W Xie, Z Zeng - International Immunopharmacology, 2022 - Elsevier
Periodontitis (PD), also known as gum disease, is a condition causing inflammatory bone
resorption and tooth loss. Regulatory T cells (Tregs) and regulatory B cells (Bregs) are vital …

Immune senescence and periodontitis: From mechanism to therapy

J Liu, R Dan, X Zhou, J Xiang, J Wang… - Journal of Leukocyte …, 2022 - academic.oup.com
Periodontitis is one of the most prevalent infectious inflammatory diseases, characterized by
irreversible destruction of the supporting tissues of teeth, which is correlated with a greater …

Enhanced immunomodulation and periodontal regeneration efficacy of subgingivally delivered progranulin‐loaded hydrogel as an adjunct to non‐surgical treatment …

W Liu, A Song, Y Wu, P Gong, J Zhao… - Journal of Clinical …, 2024 - Wiley Online Library
Aim To evaluate the effect of subgingival delivery of progranulin (PGRN)/gelatin
methacryloyl (GelMA) complex as an adjunct to scaling and root planing (SRP) on an …

Humanized mouse models for the study of periodontitis: an opportunity to elucidate unresolved aspects of its immunopathogenesis and analyze new …

C Rojas, MP García, AF Polanco… - Frontiers in …, 2021 - frontiersin.org
Periodontitis is an oral inflammatory disease in which the polymicrobial synergy and
dysbiosis of the subgingival microbiota trigger a deregulated host immune response, that …