Functional MRS studies of GABA and glutamate/Glx–A systematic review and meta-analysis

D Pasanta, JL He, T Ford, G Oeltzschner… - Neuroscience & …, 2023 - Elsevier
Functional magnetic resonance spectroscopy (fMRS) can be used to investigate
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …

[HTML][HTML] Event-related functional magnetic resonance spectroscopy

RS Koolschijn, WT Clarke, IB Ip, UE Emir, HC Barron - Neuroimage, 2023 - Elsevier
Summary Proton-Magnetic Resonance Spectroscopy (MRS) is a non-invasive brain imaging
technique used to measure the concentration of different neurochemicals.“Single-voxel” …

FSL‐MRS: An end‐to‐end spectroscopy analysis package

WT Clarke, CJ Stagg, S Jbabdi - Magnetic resonance in …, 2021 - Wiley Online Library
Purpose We introduce FSL‐MRS, an end‐to‐end, modular, open‐source MRS analysis
toolbox. It provides spectroscopic data conversion, preprocessing, spectral simulation, fitting …

Results and interpretation of a fitting challenge for MR spectroscopy set up by the MRS study group of ISMRM

M Marjańska, DK Deelchand, R Kreis… - Magnetic resonance …, 2022 - Wiley Online Library
Purpose Fitting of MRS data plays an important role in the quantification of metabolite
concentrations. Many different spectral fitting packages are used by the MRS community. A …

Diffusion‐weighted MR spectroscopy: Consensus, recommendations, and resources from acquisition to modeling

C Ligneul, C Najac, A Döring… - Magnetic resonance …, 2024 - Wiley Online Library
Brain cell structure and function reflect neurodevelopment, plasticity, and aging; and
changes can help flag pathological processes such as neurodegeneration and …

Comparison of seven modelling algorithms for γ‐aminobutyric acid–edited proton magnetic resonance spectroscopy

AR Craven, PK Bhattacharyya, WT Clarke… - NMR in …, 2022 - Wiley Online Library
Edited MRS sequences are widely used for studying γ‐aminobutyric acid (GABA) in the
human brain. Several algorithms are available for modelling these data, deriving metabolite …

Comparison of linear combination modeling strategies for edited magnetic resonance spectroscopy at 3 T

HJ Zöllner, S Tapper, SCN Hui, PB Barker… - NMR in …, 2022 - Wiley Online Library
J‐difference‐edited spectroscopy is a valuable approach for the in vivo detection of γ‐
aminobutyric‐acid (GABA) with magnetic resonance spectroscopy (MRS). A recent expert …

[HTML][HTML] Frequency drift in MR spectroscopy at 3T

SCN Hui, M Mikkelsen, HJ Zöllner, V Ahluwalia… - NeuroImage, 2021 - Elsevier
Purpose Heating of gradient coils and passive shim components is a common cause of
instability in the B 0 field, especially when gradient intensive sequences are used. The aim …

Feasibility and implications of using subject‐specific macromolecular spectra to model short echo time magnetic resonance spectroscopy data

HJ Zöllner, CW Davies‐Jenkins… - NMR in …, 2023 - Wiley Online Library
Expert consensus recommends linear‐combination modeling (LCM) of 1H MR spectra with
sequence‐specific simulated metabolite basis function and experimentally derived …

[HTML][HTML] Neurometabolic timecourse of healthy aging

T Gong, SCN Hui, HJ Zöllner, M Britton, Y Song… - Neuroimage, 2022 - Elsevier
Purpose The neurometabolic timecourse of healthy aging is not well-established, in part due
to diversity of quantification methodology. In this study, a large structured cross-sectional …