The noncanonical IKK family member TANK-binding kinase 1 (TBK1) is activated by pro-
inflammatory cytokines, but its role in controlling metabolism remains unclear. Here, we …

Background: The prevalence of overweight and obesity among children and adolescents
has increased worldwide and has reached alarming proportions. Currently, sugar …

There is no longer any serious doubt that daily habits and actions profoundly affect both
short-term and long-term health and quality of life. This concept is supported by literally …

Background Many beliefs about obesity persist in the absence of supporting scientific
evidence (presumptions); some persist despite contradicting evidence (myths). The …

Importance Short sleep duration has been recognized as a risk factor for obesity. Whether
extending sleep duration may mitigate this risk remains unknown. Objective To determine …

People with severe mental illnesses (SMIs)–including schizophrenia, major depressive
disorder (MDD) and bipolar disorder–have excessive caloric intake, a low-quality diet, and …

Energy balance is not a simple algebraic sum of energy expenditure and energy intake as
often depicted in communications. Energy balance is a dynamic process and there exist …

The objective of this non-systematic review of the literature is to highlight some of the neural
systems and pathways that are affected by the various intake-promoting aspects of the …

Background Poor sleep increases cardiovascular disease risk, and diet likely contributes to
this relationship. However, there are limited epidemiological data on the relationship …

Energy balance—that is, the relationship between energy intake and energy expenditure—
is regulated by a complex interplay of hormones, brain circuits and peripheral tissues. Leptin …