Parkinson's Disease (PD) is a common and progressive neurodegenerative disorder
characterised by motor impairments as well as non-motor symptoms. While dopamine …

Oxidative stress is a key cause of ischemic stroke and an initiator of neuronal dysfunction
and death, mainly through the overproduction of peroxides and the depletion of antioxidants …

Ferroptosis, a non-apoptotic form of programmed cell death, is triggered by oxidative stress
in cancer, heat stress in plants, and hemorrhagic stroke. A homeostatic transcriptional …

Background and Purpose—Intracerebral hemorrhage leads to disability or death with few
established treatments. Adverse outcomes after intracerebral hemorrhage result from …

Objectives N‐acetylcysteine (NAC) is a clinically approved thiol‐containing redox
modulatory compound currently in trials for many neurological and psychiatric disorders …

Regulatory programs governing neuronal death and axon regeneration in
neurodegenerative diseases remain poorly understood. In adult mice, optic nerve crush …

Mitochondrial dysfunction is associated with a spectrum of human disorders, ranging from
rare, inborn errors of metabolism to common, age-associated diseases such as …

Ferroptosis is mechanism for non-apoptotic, iron-dependent, oxidative cell death that is
characterized by glutathione consumption and lipid peroxides accumulation. Ferroptosis is …

To clarify the potential role of selenium (Se) on cerebral ischemia/reperfusion (I/R) injury, we
utilized mouse middle cerebral artery occlusion (MCAO) followed by reperfusion as an …

Over the past five decades, thanatology has come to include the study of how individual
cells in our bodies die appropriately and inappropriately in response to physiological and …