[HTML][HTML] Roles of JAK2 in aging, inflammation, hematopoiesis and malignant transformation

F Perner, C Perner, T Ernst, FH Heidel - Cells, 2019 - mdpi.com
Clonal alterations in hematopoietic cells occur during aging and are often associated with
the establishment of a subclinical inflammatory environment. Several age-related conditions …

[HTML][HTML] A review for the pharmacological effect of lycopene in central nervous system disorders

D Chen, C Huang, Z Chen - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Lycopene is an aliphatic hydrocarbon carotenoid extracted from plants like tomatoes,
papayas, and watermelons. Previous studies have shown that lycopene can exert …

Inflammatory bowel disease is associated with higher dementia risk: a nationwide longitudinal study

B Zhang, HE Wang, YM Bai, SJ Tsai, TP Su, TJ Chen… - Gut, 2021 - gut.bmj.com
Objective Increasing evidence supports reciprocal communication between the enteric and
the central nervous system in disease, termed the 'gut–brain axis'. Recent findings suggest a …

Relationship between cognitive performance and depressive symptoms in Chinese older adults: the China Health and Retirement Longitudinal Study (CHARLS)

L Zhou, X Ma, W Wang - Journal of affective disorders, 2021 - Elsevier
Abstract Background In China, an increasing number of people are aging; therefore,
attention should be paid to age-related cognitive impairment. With the increasing attention …

[HTML][HTML] Aging triggers an upregulation of a multitude of cytokines in the male and especially the female rodent hippocampus but more discrete changes in other brain …

L Porcher, S Bruckmeier, SD Burbano… - Journal of …, 2021 - Springer
Background Despite widespread acceptance that neuroinflammation contributes to age-
related cognitive decline, studies comparing protein expression of cytokines in the young …

Role of inflammation in epilepsy and neurobehavioral comorbidities: Implication for therapy

YN Paudel, MF Shaikh, S Shah, Y Kumari… - European journal of …, 2018 - Elsevier
Epilepsy is a devastating condition affecting around 70 million people worldwide. Moreover,
the quality of life of people with epilepsy (PWE) is worsened by a series of comorbidities …

Risk of neurodegenerative diseases in patients with inflammatory bowel disease: a nationwide population-based cohort study

GH Kim, YC Lee, TJ Kim, ER Kim… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims Although recent studies have reported that inflammatory
bowel disease [IBD] is associated with the development of neurodegenerative diseases via …

Incidence of dementia following hospitalization with infection among adults in the atherosclerosis risk in communities (ARIC) study cohort

B Bohn, PL Lutsey, JR Misialek, KA Walker… - JAMA Network …, 2023 - jamanetwork.com
Importance Factors associated with the risk of dementia remain to be fully understood.
Systemic infections are hypothesized to be such factors and may be targets for prevention …

[HTML][HTML] Associations between dietary and blood inflammatory indices and their effects on cognitive function in elderly Americans

W Li, S Li, Y Shang, W Zhuang, G Yan… - Frontiers in …, 2023 - frontiersin.org
Objective To determine the correlations between dietary and blood inflammation indices in
elderly Americans and their effects on cognitive function. Methods This research extracted …

Synthetic cannabinoids reduce the inflammatory activity of microglia and subsequently improve neuronal survival in vitro

AP Young, EM Denovan-Wright - Brain, Behavior, and Immunity, 2022 - Elsevier
Microglia are resident immune cells of the brain that survey the microenvironment, provide
trophic support to neurons, and clear debris to maintain homeostasis and healthy brain …