Curcumin-loaded nanoparticles: A novel therapeutic strategy in treatment of central nervous system disorders

H Yavarpour-Bali, M Ghasemi-Kasman… - International journal of …, 2019 - Taylor & Francis
Curcumin as a hydrophobic polyphenol is extracted from the rhizome of Curcuma longa.
Curcumin is widely used as a dietary spice and a topical medication for the treatment of …

[HTML][HTML] Curcumin, inflammation, and neurological disorders: How are they linked?

P Garodia, M Hegde, AB Kunnumakkara… - Integrative Medicine …, 2023 - Elsevier
Background: Despite the extensive research in recent years, the current treatment modalities
for neurological disorders are suboptimal. Curcumin, a polyphenol majorly found in …

Selenium nanoparticles with prodigiosin rescue hippocampal damage associated with epileptic seizures induced by pentylenetetrazole in rats

NE Al Omairi, A Albrakati, KF Alsharif, AS Almalki… - Biology, 2022 - mdpi.com
Simple Summary Epilepsy is a chronic neurological disease characterized by neuronal
hyper electrical activity and the development of unprovoked seizures. Although several …

Nanoformulated ellagic acid ameliorates pentylenetetrazol-induced experimental epileptic seizures by modulating oxidative stress, inflammatory cytokines and …

MA El-Missiry, AI Othman, MA Amer, M Sedki… - Metabolic Brain …, 2020 - Springer
The present study evaluated the neuroprotective and antiepileptic efficacy of ellagic acid
(EA) encapsulated in calcium-alginate nanoparticles (Ca 2+-ALG NPs) in pentylenetetrazol …

Protective effect of nanocurcumin against neurotoxicity induced by doxorubicin in rat's brain

YA Khadrawy, EN Hosny, HS Mohammed - Neurotoxicology, 2021 - Elsevier
Cognitive impairment is one of the serious side effects that cancer-treated patients suffer
from after treatment by doxorubicin (DOX). Investigating the mechanisms underlying this …

Curcumin: a review of its effects on epilepsy

F Forouzanfar, M Majeed, T Jamialahmadi… - Studies on Biomarkers …, 2021 - Springer
Central nervous system (CNS) diseases pose an enormous healthcare burden, at both an
individual and a societal level. Epilepsy has now become one of the most prevalent CNS …

Protective effects of maternal administration of curcumin and hesperidin in the rat offspring following repeated febrile seizure: Role of inflammation and TLR4

R Atabaki, A Roohbakhsh, A Moghimi… - International …, 2020 - Elsevier
Neuroinflammation has a key role in seizure generation and perpetuation in the neonatal
period, and toll-like receptor 4 (TLR4) pathway has a prominent role in neuroinflammatory …

[HTML][HTML] Mechanism of curcuma longa and its neuroactive components for the management of epileptic seizures: A systematic review

BKM Choo, MF Shaikh - Current Neuropharmacology, 2021 - ncbi.nlm.nih.gov
Curcuma longa (Turmeric) is a tropical herbaceous perennial plant of the family
Zingiberaceae and contains curcuminoids, sesquiterpenoids and monoterpenoids as its …

Antioxidant effects of Curcuma longa and its active constituent, curcumin, for the therapy of neurological disorders

BM Razavi, H Hosseinzadeh - Oxidative stress and dietary antioxidants in …, 2020 - Elsevier
Curcumin, a hydrophobic polyphenol that derived from the rhizome of Curcuma longa
(turmeric), is the main biologically active component of this plant. Different volatile oils such …

[HTML][HTML] PET imaging and neurohistochemistry reveal that curcumin attenuates brain hypometabolism and hippocampal damage induced by status epilepticus in rats

K Slowing, F Gomez, M Delgado, RF de la Rosa… - Planta …, 2023 - thieme-connect.com
Numerous preclinical studies provide evidence that curcumin, a polyphenolic phytochemical
extracted from Curcuma longa (turmeric) has neuroprotective, anti-inflammatory and …