[HTML][HTML] In silico and in vitro studies of novel cyanoacrylamides incorporating pyrazole moiety against breast and prostate carcinomas
FM Sroor, KF Mahrous, HI Shafey, NR Eid… - Medicinal Chemistry …, 2023 - Springer
We report novel cyanoacrylamide derivatives bearing the pyrazole moiety. The molecular
structures of the prepared cyanoacrylamides were confirmed by the different spectral tools …
structures of the prepared cyanoacrylamides were confirmed by the different spectral tools …
Synthesis of novel dihydropyridine, fused dihydropyridines, hexahydrobenzo[4,5]imidazo[2,1-b]quinazolines, and fused-pyrans linked to piprazine core via …
HF Hammad, AF Darweesh, MA Abdelaziz… - Synthetic …, 2023 - Taylor & Francis
Abstract The precursor, piperazine-1, 4-diylbis (2-oxoethane-2, 1-diyl) bis (4-
formylbenzoate) was prepared by reacting 1, 1'-(piperazine-1, 4-diyl) bis (2-chloroethan-1 …
formylbenzoate) was prepared by reacting 1, 1'-(piperazine-1, 4-diyl) bis (2-chloroethan-1 …
Current scenario of chalcone hybrids with antibreast cancer therapeutic applications
H Wang, J Zhu, Q Zhang, J Tang… - Archiv der …, 2024 - Wiley Online Library
Breast cancer, an epithelial malignant tumor that occurs in the terminal ducts of the breast, is
the most common female malignancy. Currently, approximately 70%–80% of breast cancer …
the most common female malignancy. Currently, approximately 70%–80% of breast cancer …
New inhibitory effect by green synthesized chalcone derivatives on the fungal deterioration of archaeological Egyptian Mummy, Egypt
NS Geweely, HM Hassaneen, RA Ali… - Polycyclic Aromatic …, 2023 - Taylor & Francis
The biodeterioration of archaeological mummies is a severe issue, where fungi are the most
significant agents deteriorating them. The inhibitory effect of [1, 2, 4] triazolo [3, 4-a] …
significant agents deteriorating them. The inhibitory effect of [1, 2, 4] triazolo [3, 4-a] …
[HTML][HTML] Novel tetrahydroisoquinolines as DHFR and CDK2 inhibitors: synthesis, characterization, anticancer activity and antioxidant properties
In this study, we synthesized new 5, 6, 7, 8-tetrahydroisoquinolines and 6, 7, 8, 9-
tetrahydrothieno [2, 3-c] isoquinolines based on 4-(N, N-dimethylamino) phenyl moiety as …
tetrahydrothieno [2, 3-c] isoquinolines based on 4-(N, N-dimethylamino) phenyl moiety as …
Cytotoxic and apoptotic effect of chalcone 5 on mouse colon cancer cells CT-26
T Ristić, J Luković, I Nikolić, M Anđelković… - Indian Journal of …, 2024 - or.niscpr.res.in
Abstract According to World Health Organization data, various forms of cancer cause around
10 million deaths each year. Nearly 2 million new colon and rectal cancer cases were …
10 million deaths each year. Nearly 2 million new colon and rectal cancer cases were …
Kalkon Türevlerinin Antikanser Mekanizmaları
Y Yıldız, F Arı - Journal of the Institute of Science and Technology, 2023 - dergipark.org.tr
Kanser; hücrelerin kontrolsüz çoğalmalarına, immün sistemin gözetiminden kaçmalarına ve
uzaktaki dokuları istila ederek yayılmalarına yol açan, metabolik değişiklikler geçirdikleri bir …
uzaktaki dokuları istila ederek yayılmalarına yol açan, metabolik değişiklikler geçirdikleri bir …
Novel tetrahydroisoquinolines as DHFR and CDK2 inhibitors: Synthesis, characterization, anticancer activity and antioxidant properties
EA Bakhite, RH Sayed, NF Sayed, HF Aly, SG Morsy… - 2023 - researchsquare.com
In this study, we synthesized new 5, 6, 7, 8-tetrahydroisoquinolines and 6, 7, 8, 9-
tetrahydrothieno [2, 3-c] isoquinolines based on 4-(N, N-dimethylamino) phenyl moiety as …
tetrahydrothieno [2, 3-c] isoquinolines based on 4-(N, N-dimethylamino) phenyl moiety as …