Targeting Anoikis Resistance as a Strategy for Cancer Therapy

Y Wang, S Cheng, JS Fleishman, J Chen, H Tang… - Drug Resistance …, 2024 - Elsevier
Anoikis, known as matrix detachment-induced apoptosis or detachment-induced cell death,
is crucial for tissue development and homeostasis. Cancer cells develop means to evade …

Self-Renewal Inhibition in Breast Cancer Stem Cells: Moonlight Role of PEDF in Breast Cancer

C Gil-Gas, M Sánchez-Díez, P Honrubia-Gómez… - Cancers, 2023 - mdpi.com
Simple Summary While more efficient cancer treatments have led to a better quality of life
and to five-year survival rates of over 85% for localized tumors, these rates remain below …

[HTML][HTML] Contribution of alternative splicing to breast cancer metastasis

X Meng, S Yang, J Zhang, H Yu - Journal of cancer metastasis and …, 2019 - ncbi.nlm.nih.gov
Alternative splicing is a major contributor to transcriptome and proteome diversity in
eukaryotes. Comparing to normal samples, about 30% more alternative splicing events were …

[HTML][HTML] LMP1 promotes nasopharyngeal carcinoma metastasis through NTRK2-mediated anoikis resistance

Z Li, Z Zhou, X Wu, Q Zhou, C Liao, Y Liu… - American journal of …, 2020 - ncbi.nlm.nih.gov
Anoikis resistance is an important mechanism that mediates tumor metastasis. Studies have
found that Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) promotes …

[HTML][HTML] Anoikis-related gene CDKN2A predicts prognosis and immune response and mediates proliferation and migration in thyroid carcinoma

M Tang, W Luo, Y Zhou, Z Zhang, Z Jiang - Translational Oncology, 2024 - Elsevier
Thyroid carcinoma (THCA) is a tumor commonly occurring in the endocrine system, and its
incidence rate is increasing yearly. Anoikis is a type of cell death involved in the …

Long Non-Coding RNA MAPK8IP1P2 Inhibits Lymphatic Metastasis of Thyroid Cancer by Activating Hippo Signaling via Sponging miR-146b-3p

X Liu, Q Fu, X Bian, Y Fu, J Xin, N Liang, S Li… - Frontiers in …, 2021 - frontiersin.org
The principal issue derived from thyroid cancer is its high propensity to metastasize to the
lymph node. Aberrant exprssion of long non-coding RNAs have been extensively reported to …

Cancer-specifically re-spliced TSG101 mRNA promotes invasion and metastasis of nasopharyngeal carcinoma

HH Chua, T Kameyama, A Mayeda, TH Yeh - International journal of …, 2019 - mdpi.com
TSG101 (Tumor susceptibility 101) gene and its aberrantly spliced isoform, termed TSG101∆
154-1054, are tightly linked to tumorigenesis in various cancers. The aberrant TSG101∆ 154 …

A novel risk model based on anoikis: Predicting prognosis and immune infiltration in cutaneous melanoma

Y Zhou, C Wang, Y Chen, W Zhang, Z Fu, J Li… - Frontiers in …, 2023 - frontiersin.org
Cutaneous melanoma (CM) is a highly aggressive malignancy with a dimal prognosis and
limited treatment options. Anoikis is believed to involve in the regeneration, migration, and …

Moonlight role of PEDF in breast cancer: self-renewal inhibition in breast cancer stem cells

C Gil-Gas, M Sánchez-Díez, P Honrubia-Gómez… - 2023 - researchsquare.com
Background: Breast cancer is the leading cause of death among females in developed
countries. Although the implementation of screening tests and the development of new …

Moonlighting Role of PEDF in Breast Cancer

C Gil-Gas, M Sánchez-Díez, P Honrubia-Gómez… - 2020 - researchsquare.com
Background: Breast cancer is the leading cause of death among females in developed
countries. Although the implementation of screening tests and the development of new …