Screening for ovarian cancer

KJ Carlson, SJ Skates, DE Singer - Annals of internal medicine, 1994 - acpjournals.org
Purpose: To critically review the available evidence for screening asymptomatic women for
ovarian cancer with ultrasonography or the CA 125 radioimmunoassay (CA 125) or both …

Multimodal approach to screening for ovarian cancer

I Jacobs, J Bridges, C Reynolds, I Stabile, P Kemsley… - The Lancet, 1988 - Elsevier
Abstract 1010 postmenopausal women were recruited for an ovarian cancer screening
programme incorporating serum CA-125 measurement and vaginal examination as initial …

[HTML][HTML] Cancer screening: a mathematical model relating secreted blood biomarker levels to tumor sizes

AM Lutz, JK Willmann, FV Cochran, P Ray… - PLoS …, 2008 - journals.plos.org
Background Increasing efforts and financial resources are being invested in early cancer
detection research. Blood assays detecting tumor biomarkers promise noninvasive and …

Considering early detection of relapsed ovarian cancer: a review of the literature

SME Geurts, F de Vegt, AM van Altena… - International Journal of …, 2011 - ijgc.bmj.com
Introduction: Patients treated for ovarian cancer with curative intent receive an intensive
follow-up program in the years after treatment. However, the aimed improved survival …

Multianalyte profiling of serum antigens and autoimmune and infectious disease molecules to identify biomarkers dysregulated in epithelial ovarian cancer

GP Bertenshaw, P Yip, P Seshaiah, J Zhao… - … Biomarkers & Prevention, 2008 - AACR
Ovarian cancer is the deadliest gynecologic cancer in the United States. When detected
early, the 5-year survival rate is 92%, although most cases remain undetected until the late …

The concomitant determination of different serum tumor markers in epithelial ovarian cancer: relevance for monitoring the response to chemotherapy and follow-up of …

P Fioretti, A Gadducci, M Ferdeghini, C Prontera… - Gynecologic …, 1992 - Elsevier
The levels of CA125, CA19. 9, CA15. 3 CA72. 4, and TATI were serially measured during
and after chemotherapy in 43 patients with epithelial ovarian cancer having elevated …

[HTML][HTML] Development and preliminary evaluation of a multivariate index assay for ovarian cancer

SD Amonkar, GP Bertenshaw, TH Chen, KJ Bergstrom… - PloS one, 2009 - journals.plos.org
Background Most women with a clinical presentation consistent with ovarian cancer have
benign conditions. Therefore methods to distinguish women with ovarian cancer from those …

Explanation of the limited correlation between tumor CA 125 content and serum CA 125 antigen levels in patients with ovarian tumors

GJ Fleuren, M Nap, JG Aalders, JB Trimbos… - Cancer, 1987 - Wiley Online Library
The concentration of the tumor marker CA 125 in tumor tissue, cyst fluid, ascites fluid, and
serum from patients with epithelial ovarian tumors was quantitated. Immunohistologic …

[HTML][HTML] Comprehensive serum profiling for the discovery of epithelial ovarian cancer biomarkers

P Yip, TH Chen, P Seshaiah, LL Stephen… - PLoS …, 2011 - journals.plos.org
FDA-cleared ovarian cancer biomarkers are limited to CA-125 and HE4 for monitoring and
recurrence and OVA1, a multivariate panel consisting of CA-125 and four additional …

Utility of pre-operative serum CA-125 in the management of uterine papillary serous carcinoma

AB Olawaiye, JA Rauh-Hain, M Withiam-Leitch… - Gynecologic …, 2008 - Elsevier
OBJECTIVE: To evaluate the usefulness of pre-operative serum CA-125 in the management
of women diagnosed with uterine papillary serous carcinoma (UPSC). We hypothesized that …