Although more than 90% of children born with congenital heart disease (CHD) survive into
adulthood, patients face significantly higher and premature morbidity and mortality. Heart …

Objective: Discuss evidence referring to the genetic role in congenital heart diseases,
whether chromosomic alterations or monogenic diseases. Data source: LILACS, PubMed …

Abstract Background Congenital heart diseases (CHDs) are the most common congenital
anomalies with an estimated prevalence of 8 in 1000 live births. CHDs occur as a result of …

Cardiovascular diseases (CVDs) constitute one of the significant causes of death worldwide.
Different pathological states are linked to CVDs, which despite interventions and treatments …

Morbidity and mortality in Down syndrome (DS) are mainly related to congenital heart
defects (CHDs). While CHDs with high prevalence in DS (typical CHDs), such as …

The frequent occurrence of congenital heart defects (CHDs) in chromosome abnormality
syndromes is well‐known, and among aneuploidy syndromes, distinctive patterns have …

Congenital heart disease (CHD) is the most common type of developmental abnormality in
humans, and is a leading cause for substantially increased morbidity and mortality in …

Following the improvements in the clinical management of patients with congenital heart
disease (CHD) and their increased survival, neurodevelopmental outcome has become an …

BACKGROUND: The pattern and risk factors for congenital heart diseases (CHD) in children
with Down syndrome (DS) vary over time. OBJECTIVES: To update knowledge of the …

Recent advances in understanding the genetic causes and anatomic subtypes of cardiac
defects have revealed new links between genetic etiology, pathogenetic mechanisms and …