Age-Related Effects of Exogenous Melatonin on Anxiety-like Behavior in C57/B6J Mice

S Nasini, S Tidei, A Shkodra, D De Gregorio… - Biomedicines, 2023 - mdpi.com
The synthesis of melatonin (MLT) physiologically decreases during aging. Treatment with
MLT has shown anxiolytic, hypnotic, and analgesic effects, but little is known about possible …

Dose-dependent beneficial effect of ketone supplement-evoked ketosis on anxiety level in female WAG/Rij rats: Sometimes less is more

E Rauch, C Ari, Z Kovács - Nutrients, 2023 - mdpi.com
While one-third of the population can be affected by anxiety disorders during their lifetime,
our knowledge of the pathophysiology of these disorders is far from complete. Previously, it …

Improving precision management of anxiety disorders: a Mendelian randomization study targeting specific gut microbiota and associated metabolites

MM Xu, WH Qiu, QY Ma, ZY Yu, WM Yang… - Frontiers in …, 2024 - frontiersin.org
Background There is growing evidence of associations between the gut microbiota and
anxiety disorders, where changes in gut microbiotas may affect brain function and behavior …

Genomics of Brain Disorders 4.0

R Cacabelos - International Journal of Molecular Sciences, 2024 - mdpi.com
Several historic, scientific events have occurred in the decade 2013–2023, in particular the
COVID-19 pandemic. This massive pathogenic threat, which has affected the world's …

[HTML][HTML] The overlapping genetic architecture of psychiatric disorders and cortical brain structure

Z Sha, V Warrier, RAI Bethlehem, LM Schultz… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Both psychiatric vulnerability and cortical structure are shaped by the cumulative effect of
common genetic variants across the genome. However, the shared genetic underpinnings …

Deciphering the Genetic Links between Psychological Stress, Autophagy, and Dermatological Health: Insights from Bioinformatics, Single-Cell Analysis, and Machine …

XL Liu, LS Chang - International Journal of Molecular Sciences, 2024 - mdpi.com
The relationship between psychological stress, altered skin immunity, and autophagy-
related genes (ATGs) is currently unclear. Psoriasis is a chronic skin inflammation of unclear …

Shared genetic links between hypothyroidism and psychiatric disorders: evidence from a comprehensive genetic analysis

J Zhou, L Zhu - Frontiers in Endocrinology, 2024 - frontiersin.org
Background Epidemiologic studies have suggested co-morbidity between hypothyroidism
and psychiatric disorders. However, the shared genetic etiology and causal relationship …

Investigating the genetic relationship between depression symptoms and Alzheimer's Disease in clinically diagnosed and proxy cases

L Gilchrist, TP Spargo, RE Green, JRI Coleman… - medRxiv, 2023 - medrxiv.org
Depression is a risk factor for the later development of Alzheimer's disease (AD), but
evidence for their genetic relationship is mixed. Assessing depression symptom specific …

Scaling of ventral hippocampal activity during anxiety

C Cerquetella, C Gontier, T Forro, JP Pfister, S Ciocchi - bioRxiv, 2023 - biorxiv.org
Background The hippocampus supports a multiplicity of functions, with the dorsal region
contributing to memory-related spatial representations, while the ventral hippocampus (vH) …

[PDF][PDF] Effectiveness of Brainwave Entrainment in Alpha Band on Working Memory, Anti-Saccade and Anxiety Level of Anxious Participants

LM Fanid, M Bayrami, HS Moghaddam, T Hashemi… - Psychological Studies, 2023 - sid.ir
The aim of this study was to determine the effect of Brainwave Entrainment in alpha band on
working memory, anti-saccade and anxiety level of anxious participants. The present study …