The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …

Clinical responses to checkpoint inhibitors used for cancer immunotherapy seemingly
require the presence of αβT cells that recognize tumour neoantigens, and are therefore …

Single-center studies have reported an association between early (before day 100)
cytomegalovirus (CMV) reactivation and decreased incidence of relapse for acute myeloid …

Allogeneic hematopoietic stem cell transplantation (HSCT) from an HLA-haploidentical
relative (haplo-HSCT) is a suitable option for children with acute leukemia (AL) either …

T lymphocytes comprise cells expressing either an αβ or a γδ TCR. The riddle how αβ TCRs
are triggered by specific peptides presented in the context of MHC was elucidated some …

Allogeneic blood or bone-marrow transplantation (alloBMT) is a potentially curative
treatment for a variety of haematological malignancies and nonmalignant diseases …

γδ T lymphocytes represent∼ 1% of human peripheral blood mononuclear cells and even
more cells in most tissues of vertebrates. Although they have important anticancer functions …

To investigate how the human γδ T cell pool is shaped during ontogeny and how it is
regenerated after transplantation of hematopoietic stem cells (HSCs), we applied an RNA …

A growing number of studies have shown that γδ T cells play a pivotal role in mediating the
clearance of tumors and pathogen-infected cells with their potent cytotoxic, cytolytic, and …

We prospectively assessed functional and phenotypic characteristics of γδ T lymphocytes up
to 7 months after HLA-haploidentical hematopoietic stem cell transplantation (haplo-HSCT) …