The biology of masculinization is fundamentally important for understanding the embryonic
developmental processes that are involved in the development of the male reproductive …

Abstract Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) is a developmental
disorder of the kidney and/or genito‐urinary tract that results in end stage kidney disease …

Rationale & Objective Hereditary nephropathies are clinically and genetically
heterogeneous disorders. For some patients, the clinical phenotype corresponds to a …

The differentiated cell types of the epithelial and mesenchymal tissue compartments of the
mature ureter of the mouse arise in a precise temporal and spatial sequence from …

Objective To explore the genetic causes of Herlyn-Werner-Wunderlich syndrome (HWWS)
using whole-exome sequencing. Design Retrospective genetic study. Setting Academic …

Background Congenital heart defects (CHD) and congenital anomalies of the kidney and
urinary tract (CAKUT) account for significant morbidity and mortality in childhood. Dozens of …

Congenital abnormalities of the kidney and urinary tract (CAKUT) form the leading cause of
pediatric end-stage renal disease. Knowledge on the molecular mechanisms that underlie …

Congenital heart disease (CHD) is one of the most common birth defects, and recent studies
indicate cilia-related mutations play a central role in the genetic etiology of CHD. As cilia are …

Objective The goal of this study was to review and analyze the medical literature for cases of
prenatal and/or postnatally diagnosed bilateral renal agenesis (BRA) and create a …

Podocytes are exquisitely fashioned kidney cells that serve an essential role in the process
of blood filtration. Congenital malformation or damage to podocytes has dire consequences …