The role of the ATP-adenosine axis in ischemic stroke
IS Schädlich, R Winzer, J Stabernack, E Tolosa… - Seminars in …, 2023 - Springer
In ischemic stroke, the primary neuronal injury caused by the disruption of energy supply is
further exacerbated by secondary sterile inflammation. The inflammatory cascade is largely …
further exacerbated by secondary sterile inflammation. The inflammatory cascade is largely …
Blocking P2RX7 attenuates ferroptosis in endothelium and reduces HG-induced hemorrhagic transformation after MCAO by inhibiting ERK1/2 and P53 signaling …
C Liu, Q Tian, J Wang, P He, S Han, Y Guo… - Molecular …, 2023 - Springer
Hyperglycemia is a risk factor for poor prognosis after acute ischemic stroke and promote the
occurrence of hemorrhagic transformation (HT). The activation of P2RX7 play an important …
occurrence of hemorrhagic transformation (HT). The activation of P2RX7 play an important …
Peripheral mechanism of cancer-induced bone pain
Y Yang, W Yang, R Zhang, Y Wang - Neuroscience Bulletin, 2023 - Springer
Cancer-induced bone pain (CIBP) is a type of ongoing or breakthrough pain caused by a
primary bone tumor or bone metastasis. CIBP constitutes a specific pain state with distinct …
primary bone tumor or bone metastasis. CIBP constitutes a specific pain state with distinct …
Effects of antidiabetic agents on platelet characteristics with implications in Alzheimer's disease: Mendelian randomization and colocalization study
Z Xie, Y Liu, M Huang, S Zhong, W Lai - Heliyon, 2024 - cell.com
Background Observational studies have found a potential link between the use of
thiazolidinediones (TZDs) and a lower risk of Alzheimer's disease (AD) development …
thiazolidinediones (TZDs) and a lower risk of Alzheimer's disease (AD) development …
[HTML][HTML] Graph neural networks-based prediction of drug gene association of P2X receptors in periodontal pain
The P2X7 receptor, a member of the P2X receptor family, plays a crucial role in various
physiological processes, particularly pain perception. Its expression across immune …
physiological processes, particularly pain perception. Its expression across immune …
Next Generation Sequencing and Electromyography Reveal the Involvement of the P2RX6 Gene in Myopathy
M Vinci, GA Vitello, D Greco, S Treccarichi… - Current Issues in …, 2024 - mdpi.com
Ion channelopathies result from impaired ion channel protein function, due to mutations
affecting ion transport across cell membranes. Over 40 diseases, including neuropathy …
affecting ion transport across cell membranes. Over 40 diseases, including neuropathy …
The potential role of connexins in the pathogenesis of atherosclerosis
K Kiełbowski, E Bakinowska, A Pawlik - International Journal of Molecular …, 2023 - mdpi.com
Connexins (Cx) are members of a protein family which enable extracellular and intercellular
communication through hemichannels and gap junctions (GJ), respectively. Cx take part in …
communication through hemichannels and gap junctions (GJ), respectively. Cx take part in …
Регуляция проагрегантной активности тромбоцитов при ингибировании циклооксигеназы у пациентов с нефролитиазом
ЭФ Баринов, ДИ Гиллер, АС Юрьева… - Регионарное …, 2023 - microcirc.ru
Аннотация Цель–установить возможность синергизма ТР-рецептора (рецептора к
тромбоксану А2) и пуринергических Р2-рецепторов при ингибировании …
тромбоксану А2) и пуринергических Р2-рецепторов при ингибировании …