Advances in chemistry and bioactivity of magnoflorine and magnoflorine-containing extracts

E Okon, W Kukula-Koch, A Jarzab, M Halasa… - International Journal of …, 2020 - mdpi.com
The review collects together some recent information on the identity and pharmacological
properties of magnoflorine, a quaternary aporphine alkaloid, that is widely distributed within …

Flavonoids derived from Exocarpium Citri Grandis inhibit LPS-induced inflammatory response via suppressing MAPK and NF-κB signalling pathways

Y Peng, M Hu, Q Lu, Y Tian, W He, L Chen… - Food and Agricultural …, 2019 - Taylor & Francis
ABSTRACT Exocarpium Citri Grandis (ECG) is used as an antitussive and anti-inflammatory
agent in traditional Chinese medicine. However, the mechanism of its anti-inflammatory …

Protopine attenuates inflammation stimulated by carrageenan and LPS via the MAPK/NF-κB pathway

MB Alam, MK Ju, YG Kwon, SH Lee - Food and Chemical Toxicology, 2019 - Elsevier
We investigated the anti-inflammatory activity of protopine (PTP) and sought to determine its
mechanism of action in LPS-stimulated BV2 cells and a carrageenan (CA)-induced mouse …

Magnoflorine—Isolation and the Anticancer Potential against NCI-H1299 Lung, MDA-MB-468 Breast, T98G Glioma, and TE671 Rhabdomyosarcoma Cancer Cells

E Okon, W Kukula-Koch, M Halasa, A Jarzab, M Baran… - Biomolecules, 2020 - mdpi.com
Magnoflorine (MGN) is a quaternary aporphine alkaloid that exhibits numerous therapeutic
properties, including neuropsychopharmacological, anti-anxiety, immunomodulatory, anti …

Structural characterization and anti-inflammatory activity of a novel neutral polysaccharide isolated from Smilax glabra Roxb.

Y Huang, Y Ye, D Xu, J Ji, J Sun, M Xu, B Xia… - International Journal of …, 2023 - Elsevier
Crude polysaccharides isolated from Smilax glabra were screened for anti-inflammatory
activity using mice ear swelling animal experiments, during which the neutral …

Small conductance calcium-activated potassium channels and nitric oxide/cGMP pathway mediate cardioprotective effects of Croton urucurana Baill. In hypertensive …

KS Lopes, AAM Marques, KGT Moreno… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Croton urucurana Baill.(Euphorbiaceae),
popularly known as 'sangue de dragão'is a Brazilian species widely used in traditional …

(−)-Hardwickiic acid and Hautriwaic acid induce Antinociception via blockade of Tetrodotoxin-sensitive voltage-dependent sodium channels

S Cai, SS Bellampalli, J Yu, W Li, Y Ji… - ACS Chemical …, 2018 - ACS Publications
For an affliction that debilitates an estimated 50 million adults in the United States, the
current chronic pain management approaches are inadequate. The Centers for Disease …

[HTML][HTML] Croton urucurana Baillon stem bark ointment accelerates the closure of cutaneous wounds in knockout IL-10 mice

TRL Casao, CG Pinheiro, MM Sarandy… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Croton urucurana Baill.(Euphorbiaceae) is a plant
used in Brazilian popular medicine for the treatment of wound healing, inflammatory …

ADMET prediction, docking, DM analysis and antibacterial screening of epoxy furan-clerodanes from Croton hypoleucus

R Velázquez-Jiménez, S González-Montiel… - Journal of Molecular …, 2023 - Elsevier
Three new epoxy-clerodanes bearing a furan ring named hypoleins D–F (1− 3) as well as
compounds know hypoleins A− C, and crotonpenes A and B were isolated from roots of …

[HTML][HTML] Flavonoid-rich fraction of Croton blanchetianus Baill.(Euphorbiaceae) leaves: Chemical profile, acute and subacute toxicities, genotoxicity and antioxidant …

AM de Oliveira, AFS de Freitas, WK Costa… - South African Journal of …, 2022 - Elsevier
Croton blanchetianus Baill, commonly known as “marmeleiro”, is native to the Brazilian
Caatinga is traditional used to treat joint pain and gastrointestinal disorders. The aim of the …