Chemotherapy for melanoma

MA Wilson, LM Schuchter - Melanoma, 2016 - Springer
Prior to the recent therapeutic advances, chemotherapy was the mainstay of treatment
options for advanced-stage melanoma. A number of studies have investigated various …

[HTML][HTML] Melanoma: molecular pathogenesis and therapeutic management

Y Liu, MS Sheikh - Molecular and cellular pharmacology, 2014 - ncbi.nlm.nih.gov
Malignant melanoma remains one of the fastest growing cancers worldwide. Although the
primary cutaneous melanoma can be managed by surgery, the advanced metastatic …

[HTML][HTML] Bioactivity screening of microalgae for antioxidant, anti-inflammatory, anticancer, anti-diabetes, and antibacterial activities

C Lauritano, JH Andersen, E Hansen… - Frontiers in marine …, 2016 - frontiersin.org
Marine microalgae are considered a potentially new and valuable source of biologically
active molecules for applications in the food industry as well as in the pharmaceutical …

Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group

AY Bedikian, M Millward, H Pehamberger… - Journal of clinical …, 2006 - ascopubs.org
Purpose Chemotherapy resistance in melanoma has been linked to antiapoptotic effects
mediated by Bcl-2 protein. We evaluated whether targeting Bcl-2 using an antisense …

Chemotherapy induces intratumoral expression of chemokines in cutaneous melanoma, favoring T-cell infiltration and tumor control

M Hong, AL Puaux, C Huang, L Loumagne, C Tow… - Cancer research, 2011 - AACR
T-cell infiltration is known to impact tumor growth and is associated with cancer patient
survival. However, the molecular cues that favor T-cell infiltration remain largely undefined …

Recent clinical trials using cisplatin, carboplatin and their combination chemotherapy drugs

T Boulikas, M Vougiouka - Oncology reports, 2004 - spandidos-publications.com
Cisplatin continues to play a central role in cancer chemotherapy in spite of its toxicity. It is
used as first-line chemotherapy against epithelial malignancies of lung, ovarian, bladder …

[HTML][HTML] Advances in the understanding of skin cancer: ultraviolet radiation, mutations, and antisense oligonucleotides as anticancer drugs

KV Laikova, VV Oberemok, AM Krasnodubets… - Molecules, 2019 - mdpi.com
Skin cancer has always been and remains the leader among all tumors in terms of
occurrence. One of the main factors responsible for skin cancer, natural and artificial UV …

Skin cancer, including related pathways and therapy and the role of luteolin derivatives as potential therapeutics

AM Juszczak, U Wöelfle, MZ Končić… - Medicinal research …, 2022 - Wiley Online Library
Cutaneous malignant melanoma is the fastest growing and the most aggressive form of skin
cancer that is diagnosed. However, its incidence is relatively scarce compared to the highest …

[HTML][HTML] Efficacy and safety of ipilimumab 3 mg/kg in patients with pretreated, metastatic, mucosal melanoma

M Del Vecchio, L Di Guardo, PA Ascierto… - European Journal of …, 2014 - Elsevier
Background Mucosal melanoma is an extremely rare and aggressive malignancy that often
remains undetected until it reaches an advanced stage, when effective treatment options are …

[HTML][HTML] Chemotherapy in cutaneous melanoma: is there still a role?

JP Pham, AM Joshua, IP da Silva, R Dummer… - Current Oncology …, 2023 - Springer
Abstract Purpose of Review In the preceding decade, the management of metastatic
cutaneous melanoma has been revolutionised with the development of highly effective …