Computer-aided detection and diagnosis for prostate cancer based on mono and multi-parametric MRI: a review

G Lemaître, R Martí, J Freixenet, JC Vilanova… - Computers in biology …, 2015 - Elsevier
Prostate cancer is the second most diagnosed cancer of men all over the world. In the last
few decades, new imaging techniques based on Magnetic Resonance Imaging (MRI) have …

Molecular subtyping of prostate cancer

SD Kaffenberger, CE Barbieri - Current opinion in urology, 2016 - journals.lww.com
We review the recent advances in the genomic understanding of human prostate cancer,
with focus on molecular subclassification. Broadly, prostate cancer can be classified based …

[HTML][HTML] Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors

DH Hovelson, AS McDaniel, AK Cani, B Johnson… - Neoplasia, 2015 - Elsevier
Next-generation sequencing (NGS) has enabled genome-wide personalized oncology
efforts at centers and companies with the specialty expertise and infrastructure required to …

Phenotypic diversity of circulating tumour cells in patients with metastatic castration‐resistant prostate cancer

AS McDaniel, R Ferraldeschi, R Krupa… - BJU …, 2017 - Wiley Online Library
Objectives To use a non‐biased assay for circulating tumour cells (CTCs) in patients with
prostate cancer (PCa) in order to identify non‐traditional CTC phenotypes potentially …

The prostate cancer genome: perspectives and potential

CE Barbieri, SA Tomlins - Urologic Oncology: Seminars and Original …, 2014 - Elsevier
Objectives Prostate cancer has a variable clinical course, and molecular characterization
has revealed striking mutational heterogeneity that may underlie the unpredictable clinical …

Computer-aided detection for prostate cancer detection based on multi-parametric magnetic resonance imaging

G Lemaitre, R Martí, M Rastgoo… - 2017 39th Annual …, 2017 - ieeexplore.ieee.org
Prostate cancer (CaP) is the second most diagnosed cancer in men all over the world. In the
last decades, new imaging techniques based on magnetic resonance imaging (MRI) have …

Frequent discordance between ERG gene rearrangement and ERG protein expression in a rapid autopsy cohort of patients with lethal, metastatic, castration‐resistant …

AM Udager, Y Shi, SA Tomlins, A Alva, J Siddiqui… - The …, 2014 - Wiley Online Library
BACKGROUND ERG rearrangements in localized prostate cancer can be detected with high
sensitivity and specificity by immunohistochemistry (IHC). However, recent data suggest that …

Computer-aided diagnosis for prostate cancer using multi-parametric magnetic resonance imaging

G Lemaitre - 2016 - u-bourgogne.hal.science
Prostate cancer (CaP) is the second most diagnosed cancer in men all over the world. CaP
growth is characterized by two main types of evolution:(i) the slow-growing tumours progress …

Prostate cancer SubtyPINg biomarKers and outcome: is clarity emERGing?

SC Smith, SA Tomlins - Clinical Cancer Research, 2014 - AACR
Molecular prostate cancer subtypes have been proposed on the basis of mutually exclusive
SPINK1 and ERG overexpression, with conflicting reports on their prognostic ability. Flavin …

Two-stage biomarker protocols for improving the precision of early detection of prostate cancer

CL Barnett, SA Tomlins, DJ Underwood… - Medical Decision …, 2017 - journals.sagepub.com
Background. New cancer biomarkers are being discovered at a rapid pace; however, these
tests vary in their predictive performance characteristics, and it is unclear how best to use …