[HTML][HTML] Understanding addiction using animal models
Drug addiction is a neuropsychiatric disorder with grave personal consequences that has an
extraordinary global economic impact. Despite decades of research, the options available to …
extraordinary global economic impact. Despite decades of research, the options available to …
From sign-tracking to attentional bias: Implications for gambling and substance use disorders
P Anselme, MJF Robinson - Progress in Neuro-Psychopharmacology and …, 2020 - Elsevier
Sign-tracking behavior in Pavlovian autoshaping is known to be a relevant index of the
incentive salience attributed to reward-related cues. Evidence has accumulated to suggest …
incentive salience attributed to reward-related cues. Evidence has accumulated to suggest …
[HTML][HTML] Choose your path: Divergent basolateral amygdala efferents differentially mediate incentive motivation, flexibility and decision-making
To survive in a complex environment, individuals form associations between environmental
stimuli and rewards to organize and optimize reward seeking behaviors. The basolateral …
stimuli and rewards to organize and optimize reward seeking behaviors. The basolateral …
The associative learning roots of affect-driven impulsivity and its role in problem gambling: A replication attempt and extension of Quintero et al.(2020)
Background and aims Negative/positive urgency (NU/PU) refers to the proneness to act
rashly under negative/positive emotions. These traits are proxies to generalized emotion …
rashly under negative/positive emotions. These traits are proxies to generalized emotion …
Under the influence: Effects of adolescent ethanol exposure and anxiety on motivation for uncertain gambling-like cues in male and female rats
SN Hellberg, JD Levit, MJF Robinson - Behavioural Brain Research, 2018 - Elsevier
Gambling disorder (GD) frequently co-occurs with alcohol use and anxiety disorders,
suggesting possible shared mechanisms. Recent research suggests reward uncertainty may …
suggesting possible shared mechanisms. Recent research suggests reward uncertainty may …
Sign tracking predicts suboptimal behavior in a rodent gambling task
M Swintosky, JT Brennan, C Koziel, JP Paulus… - …, 2021 - Springer
Rationale Reward-associated cues can promote maladaptive behavior, including risky
decision-making in a gambling setting. A propensity for sign tracking over goal tracking—ie …
decision-making in a gambling setting. A propensity for sign tracking over goal tracking—ie …
Pharmacological evidence that 5-HT2C receptor blockade selectively improves decision making when rewards are paired with audiovisual cues in a rat gambling …
WK Adams, C Barkus, JMN Ferland, T Sharp… - …, 2017 - Springer
Rationale Adding reward-concurrent cues to a rat gambling task (rGT) increases risky
choice. This cued version of the task may reflect an “addiction-like” cognitive process, more …
choice. This cued version of the task may reflect an “addiction-like” cognitive process, more …
Distinguishing between predictive and incentive value of uncertain gambling-like cues in a Pavlovian autoshaping task
MJF Robinson, C Clibanoff, CM Freeland… - Behavioural Brain …, 2019 - Elsevier
The flashing lights and celebratory sounds that dominate slot-machine gambling are
believed to promote engagement and motivation to keep playing. However, these cues are …
believed to promote engagement and motivation to keep playing. However, these cues are …
[HTML][HTML] Alter game: A study protocol on a virtual “serious game” for relapse prevention in patients with gambling disorder
Cognitive behavioral therapy (CBT) is the most successful protocol in gambling disorder
(GD) treatment. However, it presents some weaknesses, especially concerning relapse …
(GD) treatment. However, it presents some weaknesses, especially concerning relapse …
[HTML][HTML] Propensity for risky choices despite lower cue reactivity in adolescent rats
S Zeng, EFB McLaughlin, A Ramesh… - Frontiers in Behavioral …, 2023 - ncbi.nlm.nih.gov
Adolescence is a time of heightened risk-taking across species. Salient audiovisual cues
associated with rewards are a common feature of gambling environments and have been …
associated with rewards are a common feature of gambling environments and have been …