Background There has been no definitive systematic review and meta-analysis to date
examining the effect of laxatives and pharmacological therapies in chronic idiopathic …

Background: Chronic constipation is a common condition seen in family practice among the
elderly and women. There is no consensus regarding its exact definition, and it may be …

The second part of the Consensus Statement of the Italian Association of Hospital
Gastroenterologists and Italian Society of Colo-Rectal Surgery reports on the treatment of …

Polyethylene glycol (PEG) derivatives have been widely used in bio-related research.
However, PEG oligomers (with different molecular weights) or PEG based monomers (with …

OBJECTIVES Constipation is common, and its treatment is unsatisfactory. Although many
agents have been tried, there are limited data to support their use. Our aim was to undertake …

During the past decades many synthetic polymers have been studied for nanomedicine
applications and in particular as drug delivery systems. For this purpose, polymers must be …

In order to fulfill these requirements, Task Force members followed the techniques used to
produce a previous American College of Gastroenterology evidence-based monograph (4) …

OBJECTIVES: Polyethylene glycol (PEG) 3350 plus electrolytes (PEG 3350+ E) is an
established treatment for constipation and has been proposed as a treatment option for …

Chronic constipation is one of the most common digestive diseases encountered in clinical
practice. Constipation manifests as a variety of symptoms, such as infrequent bowel …

The prevalence of constipation increases with age. However, constipation is not a
physiological consequence of normal ageing. Indeed, the aetiology of constipation in older …