Tire-rubber related pollutant 6-PPD quinone: A review of its transformation, environmental distribution, bioavailability, and toxicity

X Hua, D Wang - Journal of hazardous materials, 2023 - Elsevier
The antioxidant 6-PPD has been widely used to prevent cracking and thermal oxidative
degradation and to extend the service life of tire rubber. 6-PPD quinone (6-PPDQ) is formed …

Analysis, environmental occurrence, fate and potential toxicity of tire wear compounds 6PPD and 6PPD-quinone

X Chen, T He, X Yang, Y Gan, X Qing, J Wang… - Journal of Hazardous …, 2023 - Elsevier
Abstract Tire wear compounds N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine
(6PPD) and its derivative 6PPD-quinone have been considered as emerging pollutants and …

Widespread Occurrence and Transport of p-Phenylenediamines and Their Quinones in Sediments across Urban Rivers, Estuaries, Coasts, and Deep-Sea Regions

L Zeng, Y Li, Y Sun, LY Liu, M Shen… - Environmental Science & …, 2023 - ACS Publications
p-Phenylenediamines (PPDs) are widely used as antioxidants in tire rubber, and their
derived quinone transformation products (PPD-Qs) may pose a threat to marine ecosystems …

The Tire-Derived Chemical 6PPD-quinone Is Lethally Toxic to the White-Spotted Char Salvelinus leucomaenis pluvius but Not to Two Other Salmonid Species

K Hiki, H Yamamoto - Environmental Science & Technology …, 2022 - ACS Publications
N-(1, 3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone, also known as 6PPD-
quinone (6PPD-Q), was recently identified as the toxic chemical that causes acute mortality …

First Report on the Occurrence of N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and 6PPD-Quinone as Pervasive Pollutants in Human Urine from …

B Du, B Liang, Y Li, M Shen, LY Liu… - Environmental Science & …, 2022 - ACS Publications
N-(1, 3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its quinone derivative,
6PPD-quinone (6PPD-Q), have been found to be prevalent in the environment, but there are …

Exposure to 6-PPD quinone at environmentally relevant concentrations causes abnormal locomotion behaviors and neurodegeneration in Caenorhabditis elegans

X Hua, X Feng, G Liang, J Chao… - Environmental Science & …, 2023 - ACS Publications
6-PPD quinone (6-PPDQ) can be transformed from 6-PPD through ozonation. Nevertheless,
the potential neurotoxicity of 6-PPDQ after long-term exposure and the underlying …

Environmental occurrence and toxicity of 6PPD quinone, an emerging tire rubber-derived chemical: a review

K Zoroufchi Benis, A Behnami, S Minaei… - … & Technology Letters, 2023 - ACS Publications
N-(1, 3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) is a chemical added to tires
to prevent their oxidative degradation. 6PPD is highly reactive with ozone and oxygen …

6PPD and its metabolite 6PPDQ induce different developmental toxicities and phenotypes in embryonic zebrafish

SY Zhang, X Gan, B Shen, J Jiang, H Shen… - Journal of hazardous …, 2023 - Elsevier
The automobile tire antioxidant N-(1, 3-dimethylbutyl)-N'-phenyl-p-phenylenediamine
(6PPD) and its quinone metabolite 6PPDQ have recently received much attention for their …

Oral exposure to tire rubber-derived contaminant 6PPD and 6PPD-quinone induce hepatotoxicity in mice

L Fang, C Fang, S Di, Y Yu, C Wang, X Wang… - Science of The Total …, 2023 - Elsevier
Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) is a widely used
additive for protecting various rubber products, and its product of oxidation N-(1, 3 …

Tire-derived transformation product 6PPD-quinone induces mortality and transcriptionally disrupts vascular permeability pathways in developing coho salmon

JB Greer, EM Dalsky, RF Lane… - Environmental Science & …, 2023 - ACS Publications
Urban stormwater runoff frequently contains the car tire transformation product 6PPD-
quinone, which is highly toxic to juvenile and adult coho salmon (Onchorychus kisutch) …