Bone metabolism in obesity and weight loss
SA Shapses, D Sukumar - Annual review of nutrition, 2012 - annualreviews.org
Excess body weight due to obesity has traditionally been considered to have a positive
effect on bone; however, more recent findings suggest that bone quality is compromised …
effect on bone; however, more recent findings suggest that bone quality is compromised …
Obesity and fracture in men and women: an epidemiologic perspective
CM Nielson, P Srikanth, ES Orwoll - Journal of bone and mineral …, 2012 - academic.oup.com
In Western societies, mean body weight has increased dramatically in older people, and a
similar trend exists in Asia. Yet insufficient attention has been directed to the problem of …
similar trend exists in Asia. Yet insufficient attention has been directed to the problem of …
Prevalence of vitamin D deficiency among overweight and obese US children
OBJECTIVE: Adequate vitamin D is essential for skeletal health in developing children.
Although excess body weight is associated with risk of vitamin D deficiency, the national …
Although excess body weight is associated with risk of vitamin D deficiency, the national …
Obesity is a risk factor for fracture in children but is protective against fracture in adults: a paradox
P Dimitri, N Bishop, JS Walsh, R Eastell - Bone, 2012 - Elsevier
With the rise in obesity worldwide, an important debate has developed as to whether excess
fat has a detrimental or protective effect on skeletal health in children and adults. Obese …
fat has a detrimental or protective effect on skeletal health in children and adults. Obese …
Childhood obesity, bone development, and cardiometabolic risk factors
NK Pollock - Molecular and cellular endocrinology, 2015 - Elsevier
Osteoporosis and obesity are both major public health concerns. It has long been
considered that these are distinct disorders rarely found in the same individual; however …
considered that these are distinct disorders rarely found in the same individual; however …
An epidemiological evaluation of pediatric long bone fractures—a retrospective cohort study of 2716 patients from two Swiss tertiary pediatric hospitals
Background Children and adolescents are at high risk of sustaining fractures during growth.
Therefore, epidemiological assessment is crucial for fracture prevention. The AO …
Therefore, epidemiological assessment is crucial for fracture prevention. The AO …
A randomized controlled trial of dance exergaming for exercise training in overweight and obese adolescent girls
Background Structured exergaming with prescribed moderate intensity physical activity has
reduced adiposity among adolescents. The extent to which adolescents reduce adiposity …
reduced adiposity among adolescents. The extent to which adolescents reduce adiposity …
Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice
GV Halade, A El Jamali, PJ Williams, RJ Fajardo… - Experimental …, 2011 - Elsevier
Clinical evidence indicates that fat is inversely proportional to bone mass in elderly obese
women. However, it remains unclear whether obesity accelerates bone loss. In this report …
women. However, it remains unclear whether obesity accelerates bone loss. In this report …
High-fat diet causes bone loss in young mice by promoting osteoclastogenesis through alteration of the bone marrow environment
Obesity is a severe health problem in children, afflicting several organ systems including
bone. However, the role of obesity on bone homeostasis and bone cell function in children …
bone. However, the role of obesity on bone homeostasis and bone cell function in children …
Regulation of early adipose commitment by Zfp521
While there has been significant progress in determining the transcriptional cascade
involved in terminal adipocyte differentiation, less is known about early events leading to …
involved in terminal adipocyte differentiation, less is known about early events leading to …