Simple Summary We herein reviewed the current evidence for the role of microRNAs
(miRNAs) in the mechanism of chemoresistance in pancreatic cancer. Pancreatic cancer …

Pancreatic cancer is a highly lethal malignancy and a fourth leading cause of cancer-related
death in the United States. Poor survival of pancreatic cancer patients is largely because of …

Pancreatic ductal adenocarcinoma (PDAC) is the primary reason for cancer-related deaths
in the US. Genetic mutations, drug resistance, the involvement of multiple signaling …

Hypoxic microenvironment, a common feature of pancreatic cancer, is associated with tumor
proliferation, metastasis and epithelial-mesenchymal transition (EMT) changes. In recent …

Increasing evidence indicates that most of the tumors are sustained by a distinct population
of cancer stem cells (CSCs), which are responsible for growth, metastasis, invasion, and …

Purpose: Subconjunctival injection of antagomir-21 attenuates the progression of corneal
neovascularization. We examined the underlying mechanism by investigating the regulation …

Patients with pancreatic cancer have a poor prognosis with a median survival of 4-6 mo and
a 5-year survival of less than 5%. Despite therapy with gemcitabine, patient survival does …

Cancer stem cells are a subset of cells that are responsible for cancer initiation and relapse.
They are generally resistant to the current anticancer agents. Successful anticancer therapy …

Cancer cells are different from normal cells in regard to phenotypic and functional
expression. Cancer is the outcome of aberrant gene expression affecting various cellular …

The epigenetic regulation of cancer cells by small non-coding RNA molecules, the
microRNAs (miRNAs), has raised particular interest in the field of oncology. These miRNAs …