Bone remodeling is tightly controlled by osteoclast-mediated bone resorption and osteoblast-
mediated bone formation. Fine tuning of the osteoclast–osteoblast balance results in strict …

Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival
inflammation and bone loss. Periodontitis is associated with various systemic diseases …

Pyroptosis is a caspase-dependent process relevant to the understanding of beneficial host
responses and medical conditions for which inflammation is central to the pathophysiology …

Chronic periapical periodontitis (CAP) is a typical oral disease in which periodontal
inflammation caused by an odontogenic infection eventually leads to bone loss …

The oral cavity is inhabited by a wide spectrum of microbial species, and their colonization is
mostly based on commensalism. These microbes are part of the normal oral flora, but there …

Recently, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic
agent of coronavirus disease 2019 (COVID-19), has led to a worldwide pandemic with …

Infection with specific pathogens and alterations in tissue commensal microbial composition
are intricately associated with the development of many human cancers. Likewise, dysbiosis …

Periodontitis is known to be initiated by periodontal microbiota derived from biofilm
formation. The microbial dysbiotic changes in the biofilm trigger the host immune and …

Inflammation is a driven force in modulating microbial communities, but little is known on the
interplay between colonizing microorganisms and the immune response in periodontitis …

Fusobacterium nucleatum is a common oral opportunistic bacterium that can cause different
infections. In recent years, studies have shown that F. nucleatum is enriched in lesions in …