Antioxidant intervention against male infertility: Time to design novel strategies

C Ávila, JI Vinay, M Arese, L Saso, R Rodrigo - Biomedicines, 2022 - mdpi.com
Infertility is a highly prevalent condition, affecting 9–20% of couples worldwide. Among the
identifiable causes, the male factor stands out in about half of infertile couples, representing …

Intervention of taurine on fatty acid profiles, oxidative injury and autophagy status in the muscle of rice field eel (Monopterus albus) fed oxidized fish oil

M Cai, W Chu, J Wang, C Shao, Y Hu, C Che, J Zhang… - Aquaculture, 2022 - Elsevier
Fish oil is the primary oil source in the aquatic feed, easily oxidized in feed production and
storage. To avoid the potentially negative effects caused by oil oxidation and diversify the …

Systemic actions of sglt2 inhibition on chronic mtor activation as a shared pathogenic mechanism between alzheimer's disease and diabetes

GD Stanciu, RN Rusu, V Bild, LE Filipiuc, BI Tamba… - Biomedicines, 2021 - mdpi.com
Alzheimer's disease (AD) affects tens of millions of people worldwide. Despite the advances
in understanding the disease, there is an increased urgency for pharmacological …

Ferulic acid prevents cyclosporine-induced nephrotoxicity in rats through exerting anti-oxidant and anti-inflammatory effects via activation of Nrf2/HO-1 signaling and …

A Nouri, K Ghatreh-Samani, H Amini-Khoei… - Naunyn-Schmiedeberg's …, 2022 - Springer
Cyclosporine is one of the main immunosuppressive agents used in the treatment of
autoimmune diseases or transplantation. Despite the favorable effects, cyclosporine …

Ganoderic acid improves 5-fluorouracil-induced cognitive dysfunction in mice

A Abulizi, J Ran, Y Ye, Y An, Y Zhang, Z Huang… - Food & Function, 2021 - pubs.rsc.org
5-Fluorouracil (5-FU) is a chemotherapeutic drug with a good anti-cancer effect on various
types of cancers, such as colorectal cancer and breast cancer. However, previous studies …

Helicobacter pylori infection induces autophagy via ILK regulation of NOXs-ROS-Nrf2/HO-1-ROS loop

B Li, X Lv, Z Xu, J He, SS Liu, X Zhang, X Tong… - World Journal of …, 2023 - Springer
Reactive oxygen species (ROS) can regulate the occurrence of autophagy, and effective
control of the balance between ROS and autophagy may be an important strategy for …

Curcumin activation of nuclear factor E2-related factor 2 gene (Nrf2): Prophylactic and therapeutic effect in nonalcoholic steatohepatitis (NASH)

NM Abd El-Hameed, SA Abd El-Aleem, MA Khattab… - Life Sciences, 2021 - Elsevier
Backgrounds Modern dietary habits have been associated with Nonalcoholic Steatohepatitis
(NASH). Curcumin is a natural herbal found to suppress cellular oxidative states and could …

Sulforaphane enhances long-term potentiation and ameliorate scopolamine-induced memory impairment

HS Park, ES Hwang, GY Choi, HB Kim, KS Park… - Physiology & …, 2021 - Elsevier
Increases in human life expectancy have led to increases in the prevalence of senile
dementia and neurodegenerative diseases. This is a major problem because there are no …

The therapeutic potential of mitochondrial transplantation for the treatment of neurodegenerative disorders

C Espino De la Fuente-Munoz, C Arias - Reviews in the …, 2021 - degruyter.com
Mitochondrial activity is essential to support neural functions, and changes in the integrity
and activity of the mitochondria can contribute to synaptic damage and neuronal death …

Spatial tissue proteomics reveals distinct landscapes of heterogeneity in cutaneous papillomavirus‐induced keratinocyte carcinomas

M Schäfer, M Schneider, T Müller… - Journal of medical …, 2023 - Wiley Online Library
Infection with certain cutaneous human papillomaviruses (HPV), in conjunction with chronic
ultraviolet (UV) exposure, are the major cofactors of non‐melanoma skin cancer (NMSC) …