The biofilm is a bacterial colony wrapped in an auto-produced polymer matrix of
polysaccharides, proteins, and DNA. Bacterial biofilms cause persistent infections because …

Diabetic foot ulcers (DFUs) are a serious complication from diabetes mellitus, with a huge
economic, social and psychological impact on the patients' life. One of the main reasons why …

The bubbling community of microorganisms, consisting of diverse colonies encased in a self-
produced protective matrix and playing an essential role in the persistence of infection and …

Biofilms play a major role in delaying chronic wounds from healing. A wound infiltrated with
biofilm, or “critically colonised” wound, may become clinically infected if the number of …

The Centers for Disease Control and Prevention estimate for human infectious diseases
caused by bacteria with a biofilm phenotype is 65 percent and the National Institutes of …

Pseudomonas aeruginosa, a Gram-negative, rod-shaped bacterium causes widespread
diseases in humans. This bacterium is frequently related to nosocomial infections such as …

Wound biofilms represent a particularly challenging problem in modern medicine. They are
increasingly antibiotic resistant and can prevent the healing of chronic wounds. However …

The presence of non-viable tissue in a chronic wound presents a barrier against effective
wound healing, hence removal facilitates healing and reduces areas where microorganisms …

Background Biofilms are ubiquitous, and have been observed in both acute and chronic
wounds. Their role in wound healing and infection, however, remains controversial. The aim …

Significance: Infections can significantly delay the healing process in chronic wounds,
placing an enormous economic burden on health care resources. Identification of infection …