Enniatin B (ENN B) and Beauvericin (BEA) are cyclohexadepsipeptides that can be isolated
from Fusarium and Beauveria bassiana, respectively. Both compounds are cytotoxic and …

Cancer remains a formidable global health challenge, and as such, investigators are
constantly exploring underlying mechanisms that drive its progression. One area of interest …

Pulmonary fibrosis (PF) associated with systemic sclerosis (SSc) results in significant
morbidity and mortality. We previously reported that insulin-like growth factor-II (IGF-II) is …

Alzheimer's disease (AD) is the most common form of dementia, however incurable so far. It
is widely accepted that aggregated amyloid β (Aβ) peptides play a crucial role for the …

While human in vitro embryo production is generally performed individually, animal models
have shown that culturing embryos in groups improves blastocyst yield and quality …

Proteolytic activity is pivotal in maintaining cell homeostasis and function. In pathological
conditions such as cancer, it covers a key role in tumor cell viability, spreading to distant …

Cathepsins are one of the most abundant proteases within the lysosomes with diverse
physiological effects ranging from immune responses, cell death and intracellular protein …

Glioblastoma (GBM) is a deadly brain tumor, and the kinesin motor KIF11 is an attractive
therapeutic target with roles in proliferation and invasion. Resistance to KIF11 inhibitors …

As a promising acaricide and potentially hazardous material, the defense mechanisms of
non-target organisms to its exposure are unknown. This study investigates the bioavailability …

Objective The dopaminergic nigrostriatal neurons (DA cells) in healthy people present a
slow degeneration with aging, which produces cellular debris throughout life. About 2%–5 …