Dihydroxyacetone (DHA) is the active ingredient in sunless tanning products and a
combustion product from e-juices in electronic cigarettes (e-cigarettes). DHA is rapidly …

This study was aimed at identifying molecular markers associated with the pathogenesis of
sudden cardiac death (SCD). It provides a proteomic analysis of human left anterior …

Background Helicobacter pylori is a key agent for causing gastric complications linked with
gastric disorders. In response to infection, host cells stimulate autophagy to maintain cellular …

Antigens presented on the cell surface have been subjected to multiple biological
processes. Among them, C-terminal antigen processing constitutes one of the main …

Chronic wounds are a significant health problem worldwide. However, nothing is known
about how chronic wounds initiate and develop. Here we use a chronic wound model in …

The homeostasis of extracellular matrix (ECM) and actin dynamics in the trabecular
meshwork (TM) outflow pathway plays a critical role in intraocular pressure (IOP) regulation …

The endolysosomal system specializes in degrading cellular components and is crucial to
maintaining homeostasis and adapting rapidly to metabolic and environmental cues. Cells …

This study examined autophagy-lysosome pathway (ALP) perturbations in synovial
monocytes/macrophages from patients with gouty arthritis (GA) and the associations of ALP …

Loss of vision due to progressive retinal degeneration is a hallmark of neuronal ceroid
lipofuscinoses (NCL), a group of fatal neurodegenerative lysosomal storage diseases …

Currently, there are several treatments approaches available for lung cancer; however,
patients who develop drug resistance or have poor survival rates urgently require new …