Nuclear receptors are ligand-activated transcription factors and include the receptors for
steroid hormones, lipophilic vitamins, sterols, and bile acids. These receptors serve as …

Peripheral metabolism of thyroid hormones is a critical component of the impact these
hormones have on intracellular function. Thyroid hormones can be metabolized in …

Thyroxine hormone has been recognised since the early part of the nineteenth century and
levothyroxine has been available since the mid-nineteenth century as a replacement for …

Dementia is a neurological disorder that is spreading with increasing human lifespan. In this
neurological disorder, memory and cognition are declined and eventually impaired. Various …

Objective To quantify the effect of levothyroxine dose on risk of fractures in older adults.
Design Nested case-control study. Setting Population based health databases, Ontario …

We report the development of a surface-enhanced Raman scattering (SERS)-based lateral
flow immunoassay (LFIA) sensor for the highly sensitive detection of thyroid-stimulating …

Thyroid hormones (THs) have a wide and important range of effects within the central
nervous system beginning from fetal life and continuing throughout the adult life. Thyroid …

Hepatic microsomal enzymes play an important role in thyroid hormone homeostasis.
Glucuronidation of thyroxine is the rate limiting step in the biliary excretion of thyroxine in the …

The effect of phenobarbital on thyroid function and the metabolism and biliary excretion of
thyroxine in rats was determined. Phenobarbital, administered for 2 weeks at a dose of 100 …

Background Several endocrine-disrupting metals may affect thyroid function, but the few
available studies of exposure during pregnancy and thyroid hormones are inconclusive …