Breathlessness and the brain: the role of expectation

LL Marlow, OK Faull, SL Finnegan… - Current opinion in …, 2019 - journals.lww.com
A person's expectations and mood are major contributors to the function of the brain
networks that generate perceptions of breathlessness. Breathlessness, therefore, arises …

The physiology and pathophysiology of exercise hyperpnea

JA Dempsey, JA Neder, DB Phillips… - Handbook of clinical …, 2022 - Elsevier
In health, the near-eucapnic, highly efficient hyperpnea during mild-to-moderate intensity
exercise is driven by three obligatory contributions, namely, feedforward central command …

Pulmonary rehabilitation for adults with chronic respiratory disease: an official American Thoracic Society clinical practice guideline

CL Rochester, JA Alison, B Carlin… - American Journal of …, 2023 - atsjournals.org
Background: Despite the known benefits of pulmonary rehabilitation (PR) for patients with
chronic respiratory disease, this treatment is underused. Evidence-based guidelines should …

Exertional dyspnoea in patients with mild‐to‐severe chronic obstructive pulmonary disease: neuromechanical mechanisms

MD James, DB Phillips, SG Vincent… - The Journal of …, 2022 - Wiley Online Library
In patients with chronic obstructive pulmonary disease (COPD), exertional dyspnoea
generally arises when there is imbalance between ventilatory demand and capacity, but the …

[HTML][HTML] Identification of inflammation-related biomarker Lp-PLA2 for patients with COPD by comprehensive analysis

M Deng, Y Yin, Q Zhang, X Zhou, G Hou - Frontiers in immunology, 2021 - frontiersin.org
Purpose Chronic obstructive pulmonary disease (COPD) is a complex and persistent lung
disease and lack of biomarkers. The aim of this study is to screen and verify effective …

Residual exertional dyspnea in cardiopulmonary disease

JA Neder - Annals of the American Thoracic Society, 2020 - atsjournals.org
In cardiopulmonary medicine, residual exertional dyspnea (RED) can be defined by the
persistence of limiting breathlessness in a patient who is already under the best available …

Cardiopulmonary exercise testing applied to respiratory medicine: Myths and facts

JA Neder - Respiratory Medicine, 2023 - Elsevier
Cardiopulmonary exercise testing (CPET) remains poorly understood and, consequently,
largely underused in respiratory medicine. In addition to a widespread lack of knowledge of …

Oral formulation angiotensin-(1-7) therapy attenuates pulmonary and systemic damage in mice with emphysema induced by elastase

AC Bastos, GS Magalhães, JF Gregório, NA Matos… - Immunobiology, 2020 - Elsevier
Abstract Angiotensin-(1-7)[Ang-(1-7)], a peptide of the renin-angiotensin system, has anti-
inflammatory, anti-fibrotic and antiproliferative effects in acute or chronic inflammatory …

Capnography-assisted learned, monitored (CALM) breathing therapy for dysfunctional breathing in COPD: A bridge to pulmonary rehabilitation

A Norweg, B Hofferber, C Oh, M Spinner… - Contemporary Clinical …, 2023 - Elsevier
Background Although dyspnea is a primary symptom of chronic obstructive pulmonary
disease (COPD), its treatment is suboptimal. In both COPD and acute anxiety, breathing …

Impact of fan therapy during exercise on breathlessness and recovery time in patients with COPD: a pilot randomised controlled crossover trial

A Long, M Cartwright, CC Reilly - ERJ open research, 2021 - Eur Respiratory Soc
Background Patients with COPD reduce physical activity to avoid the onset of
breathlessness. Fan therapy can reduce breathlessness at rest, but the efficacy of fan …