Assessing anhedonia in depression: Potentials and pitfalls

SJ Rizvi, DA Pizzagalli, BA Sproule… - … & Biobehavioral Reviews, 2016 - Elsevier
The resurgence of interest in anhedonia within major depression has been fuelled by
clinical trials demonstrating its utility in predicting antidepressant response as well as recent …

Characterizing anhedonia: A systematic review of neuroimaging across the subtypes of reward processing deficits in depression

A Borsini, ASJ Wallis, P Zunszain, CM Pariante… - Cognitive, Affective, & …, 2020 - Springer
Anhedonia is a key symptom of major depressive disorder (MDD) and comprises
behavioural deficits in three reward processing subtypes: reward liking, reward wanting, and …

Reconceptualizing anhedonia: novel perspectives on balancing the pleasure networks in the human brain

K Rømer Thomsen, PC Whybrow… - Frontiers in behavioral …, 2015 - frontiersin.org
Anhedonia, the lack of pleasure, has been shown to be a critical feature of a range of
psychiatric disorders. Yet, it is currently measured primarily through subjective self-reports …

Personalized medicine in psychiatry: problems and promises

U Ozomaro, C Wahlestedt, CB Nemeroff - BMC medicine, 2013 - Springer
The central theme of personalized medicine is the premise that an individual's unique
physiologic characteristics play a significant role in both disease vulnerability and in …

The assessment of anhedonia in clinical and non-clinical populations: Further validation of the Snaith–Hamilton Pleasure Scale (SHAPS)

IHA Franken, E Rassin, P Muris - Journal of affective disorders, 2007 - Elsevier
BACKGROUND: Anhedonia, the inability to experience pleasure, is a major endophenotype
of depression. In addition to this, it is an important clinical feature of schizophrenia and …

Neural representation of reward in recovered depressed patients

C McCabe, PJ Cowen, CJ Harmer - Psychopharmacology, 2009 - Springer
Introduction Anhedonia, a loss of interest and pleasure in normally rewarding stimuli, is a
key diagnostic criterion for major depression. It has been suggested that deficits in the …

Anhedonia and substance dependence: clinical correlates and treatment options

DS Hatzigiakoumis, G Martinotti… - Frontiers in …, 2011 - frontiersin.org
Anhedonia is a condition in which the capacity of experiencing pleasure is totally or partially
lost, and it refers to both a state symptom in various psychiatric disorders and a personality …

Development and validation of the Dimensional Anhedonia Rating Scale (DARS) in a community sample and individuals with major depression

SJ Rizvi, LC Quilty, BA Sproule, A Cyriac, RM Bagby… - Psychiatry …, 2015 - Elsevier
Anhedonia, a core symptom of Major Depressive Disorder (MDD), is predictive of
antidepressant non-response. In contrast to the definition of anhedonia as a “loss of …

Individual differences in trait anhedonia: a structural and functional magnetic resonance imaging study in non-clinical subjects

PO Harvey, J Pruessner, Y Czechowska… - Molecular …, 2007 - nature.com
Anhedonia, the reduced capacity to gain pleasure from pleasurable experiences, is a key
symptom of major depression and schizophrenia. Reduced hedonic capacity can also be …

Enduring deficits in brain reward function after chronic social defeat in rats: susceptibility, resilience, and antidepressant response

A Der-Avakian, MS Mazei-Robison, JP Kesby… - Biological …, 2014 - Elsevier
Background Anhedonia, or diminished interest or pleasure in rewarding activities,
characterizes depression and reflects deficits in brain reward circuitries. Social stress …