Abstract “Neurodegenerative disorder” is an umbrella term for a group of fatal progressive
neurological illnesses characterized by neuronal loss and inflammation. Interleukin-6 (IL-6) …

Abstract Parkinson's disease (PD), the second most common neurodegenerative disease, is
clinically characterized by both motor and non-motor symptoms. Although overall great …

Background Neuroinflammation has been widely accepted as a cause of the degenerative
process. Increasing interest has been devoted to developing intervening therapeutics for …

Background: One of the typical symptoms of diabetes mellitus patients was memory
impairment, which was followed by gradual cognitive deterioration and for which there is no …

Simple Summary Vitamin C (Vit C), also called ascorbic acid, is a nutrient present in many
foods, particularly citrus fruits and green vegetables. Inadequate dietary Vit C intake causes …

Previous studies have shown that the ATP-P2X4 receptor signaling pathway mediates the
activation of the Nod-like receptor family protein 3 (NLRP3) inflammasome. The NLRP3 …

Macroautophagy, an evolutionary conserved catabolic process in the eukaryotic cell,
regulates cellular homeostasis and plays a decisive role in self-engulfing proteins, protein …

Clinical and epidemiological research shows that people with diabetes mellitus frequently
experience diabetic cognitive impairment. Schisandrin A (SchA), one of the lignans found in …

Recent evidence suggests that misfolding, clumping, and accumulation of proteins in the
brain may be common causes and pathogenic mechanism for several neurological …

In this study, we investigated autophagy, glial activation status, and corticotropin releasing
factor (CRF) signaling in the brains of mice after 5 days of sleep fragmentation (SF). Three …