[HTML][HTML] The mechanisms for pattern completion and pattern separation in the hippocampus
ET Rolls - Frontiers in systems neuroscience, 2013 - frontiersin.org
The mechanisms for pattern completion and pattern separation are described in the context
of a theory of hippocampal function in which the hippocampal CA3 system operates as a …
of a theory of hippocampal function in which the hippocampal CA3 system operates as a …
New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?
The integration of adult-born neurons into the circuitry of the adult hippocampus suggests an
important role for adult hippocampal neurogenesis in learning and memory, but its specific …
important role for adult hippocampal neurogenesis in learning and memory, but its specific …
[HTML][HTML] Young dentate granule cells mediate pattern separation, whereas old granule cells facilitate pattern completion
T Nakashiba, JD Cushman, KA Pelkey, S Renaudineau… - Cell, 2012 - cell.com
Adult-born granule cells (GCs), a minor population of cells in the hippocampal dentate
gyrus, are highly active during the first few weeks after functional integration into the …
gyrus, are highly active during the first few weeks after functional integration into the …
Hippocampal oxytocin receptors are necessary for discrimination of social stimuli
Oxytocin receptor (Oxtr) signaling in neural circuits mediating discrimination of social stimuli
and affiliation or avoidance behavior is thought to guide social recognition. Remarkably, the …
and affiliation or avoidance behavior is thought to guide social recognition. Remarkably, the …
[PDF][PDF] CA3 retrieves coherent representations from degraded input: direct evidence for CA3 pattern completion and dentate gyrus pattern separation
JP Neunuebel, JJ Knierim - Neuron, 2014 - cell.com
Theories of associative memory suggest that successful memory storage and recall depend
on a balance between two complementary processes: pattern separation (to minimize …
on a balance between two complementary processes: pattern separation (to minimize …
Hippocampal replay in the awake state: a potential substrate for memory consolidation and retrieval
The hippocampus is required for the encoding, consolidation and retrieval of event
memories. Although the neural mechanisms that underlie these processes are only partially …
memories. Although the neural mechanisms that underlie these processes are only partially …
[PDF][PDF] A multiplexed, heterogeneous, and adaptive code for navigation in medial entorhinal cortex
Medial entorhinal grid cells display strikingly symmetric spatial firing patterns. The clarity of
these patterns motivated the use of specific activity pattern shapes to classify entorhinal cell …
these patterns motivated the use of specific activity pattern shapes to classify entorhinal cell …
Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders
MA Kheirbek, KC Klemenhagen, A Sahay… - Nature neuroscience, 2012 - nature.com
Although an influence of adult neurogenesis in mediating some of the effects of
antidepressants has received considerable attention in recent years, much less is known …
antidepressants has received considerable attention in recent years, much less is known …
[PDF][PDF] Re-evaluating circuit mechanisms underlying pattern separation
NA Cayco-Gajic, RA Silver - Neuron, 2019 - cell.com
When animals interact with complex environments, their neural circuits must separate
overlapping patterns of activity that represent sensory and motor information. Pattern …
overlapping patterns of activity that represent sensory and motor information. Pattern …
A computational theory of hippocampal function, and tests of the theory: new developments
The aims of the paper are to update Rolls' quantitative computational theory of hippocampal
function and the predictions it makes about the different subregions (dentate gyrus, CA3 and …
function and the predictions it makes about the different subregions (dentate gyrus, CA3 and …