Hallucinogens (psychedelics) are psychoactive substances that powerfully alter perception,
mood, and a host of cognitive processes. They are considered physiologically safe and do …

Serotonergic psychedelics are substances that induce alterations in mood, perception, and
thought, and have the activation of serotonin (5‐HT) 2A receptors (5‐HT2ARs) as a main …

Serotonergic hallucinogens such as lysergic acid diethylamide (LSD) induce head twitches
in rodents via 5-HT 2A receptor activation. The goal of the present investigation was to …

A series of conformationally restricted analogues of the hallucinogenic phenethylamine 1 (2,
5-dimethoxy-4-bromophenethylamine, 2C-B) was synthesized to test several hypotheses …

This paper describes some of the new classes of 'designer drugs' being encountered today
by forensic scientists and law enforcement agencies in Europe, the United States, and …

The title compound ([3H] INBMeO) was prepared by an O, O-dimethylation reaction of a t-
BOC protected diphenolic precursor using no carrier added tritiated iodomethane in DMF …

A metal-free tandem Friedel–Crafts/lactonization reaction to 3, 3-diaryl or 3-alkyl-3-aryl
benzofuranones catalyzed by HClO4 was reported. A variety of tertiary α-hydroxy acid esters …

On the basis of the structural similarity of our previous 5-HT2C agonists with the melatonin
receptor agonist tasimelteon and the putative biological cross-talk between serotonergic and …

Introduction Many countries have specific legislation, such as the Controlled Substances Act
(1970) in the United States and the Misuse of Drugs Act (1971) in the United Kingdom to …

In recent years, rigid analogs of phenylalkylamine hallucinogens have appeared as
recreational drugs. Examples include 2-(8-bromo-2, 3, 6, 7-tetrahydrobenzo [1, 2-b: 4, 5-b′] …