[PDF][PDF] Fundamental biological features of spaceflight: advancing the field to enable deep-space exploration

E Afshinnekoo, RT Scott, MJ MacKay, E Pariset… - Cell, 2020 - cell.com
Research on astronaut health and model organisms have revealed six features of
spaceflight biology that guide our current understanding of fundamental molecular changes …

Common Pathophysiology in Cancer, Atrial Fibrillation, Atherosclerosis, and Thrombosis: JACC: CardioOncology State-of-the-Art Review

O Leiva, D AbdelHameid, JM Connors, CP Cannon… - Cardio Oncology, 2021 - jacc.org
Cardiovascular disease and cancer are the 2 leading causes of death worldwide. Emerging
evidence suggests common mechanisms between cancer and cardiovascular disease …

The cancer patient and cardiology

JL Zamorano, C Gottfridsson… - European journal of …, 2020 - Wiley Online Library
Advances in cancer treatments have improved clinical outcomes, leading to an increasing
population of cancer survivors. However, this success is associated with high rates of short …

Reverse cardio‐oncology: cancer development in patients with cardiovascular disease

JP Aboumsallem, J Moslehi… - Journal of the American …, 2020 - Am Heart Assoc
Overwhelming epidemiological evidence demonstrate that cardiovascular disease and
cancer represent major health burdens in the United States, and they are the leading causes …

Cardio-onco-metabolism: metabolic remodelling in cardiovascular disease and cancer

A Karlstaedt, J Moslehi, RA de Boer - Nature Reviews Cardiology, 2022 - nature.com
Cardiovascular disease and cancer are the two leading causes of morbidity and mortality in
the world. The emerging field of cardio-oncology has revealed that these seemingly …

Clinical insights into the origins of thrombosis in myeloproliferative neoplasms

AR Moliterno, YZ Ginzburg… - Blood, The Journal of the …, 2021 - ashpublications.org
Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs), polycythemia
vera, essential thrombocythemia, and primary myelofibrosis, are hematopoietic stem cell …

Circulating stem cells and cardiovascular outcomes: from basic science to the clinic

GP Fadini, A Mehta, DS Dhindsa… - European heart …, 2020 - academic.oup.com
The cardiovascular and haematopoietic systems have fundamental inter-relationships
during development, as well as in health and disease of the adult organism. Although …

The evolution of hematopoietic cells under cancer therapy

O Pich, A Cortes-Bullich, F Muiños… - Nature …, 2021 - nature.com
Chemotherapies may increase mutagenesis of healthy cells and change the selective
pressures in tissues, thus influencing their evolution. However, their contributions to the …

Cardiovascular disease among patients with AML and CHIP-related mutations

O Calvillo-Argüelles, A Schoffel, JM Capo-Chichi… - Cardio Oncology, 2022 - jacc.org
Background Clonal hematopoiesis of indeterminate potential (CHIP) is a novel
cardiovascular disease (CVD) risk factor in individuals without acute myeloid leukemia …

Clonal haematopoiesis of indeterminate potential: associations with heart failure incidence, clinical parameters and biomarkers

C Shi, JP Aboumsallem, N Suthahar… - European Journal of …, 2023 - Wiley Online Library
Aim We aimed to analyse the association of clonal haematopoiesis of indeterminate
potential (CHIP) with incident heart failure (HF) in a European population cohort. Methods …