Clonal hematopoiesis of indeterminate potential (CHIP) describes recurrent somatic gene
mutations in the blood of healthy individuals, associated with higher risk for hematological …

Introduction Clonal hematopoiesis, a precursor to myelodysplastic syndromes (MDS),
constitutes a novel cardiovascular disease (CVD) risk factor, causing growing interest in …

Chronic myeloid leukemia (CML) has long been considered as a model of cancer caused by
a single-driver genetic lesion (BCR/ABL1 rearrangement) that codes for a unique, gain-of …

Cancer and cardiovascular disease share several risk factors. Clonal heamatopoiesis, a
novel risk factor associated with both diseases, has received increasing attention in the …

Clonal hematopoiesis (CH) is a clonally expanded population of hematopoietic stem cells
carrying somatic mutations that differentiate through multilineage hematopoiesis to form …

In normal dividing tissues, cell homeostasis is maintained by rare cellular elements, the stem
cells, that have the unique property of self-renewal and differentiation to generate a …

Резюме Прогресс, достигнутый за последнее десятилетие в области кардиогенетики,
ознаменовался, главным образом, работами, основанными на оценке наследуемых …

Clonal haematopoiesis of indeterminate potential (CHIP) represents a recently identified
overlap between cancer and cardiovascular disease (CVD). CHIP develops as a result of …

Establishment and preliminary assessment of a nomogram model for the risk of early
complication of symptomatic heart failure in de novo patients with acute myeloid leukemia …

The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is a major
regulator of innate immune responses to both endogenous and exogenous stimuli. Upon …