Type 2 diabetes mellitus (T2DM) is a worldwide epidemic, which by all predictions will only
increase. To help in combating the devastating array of phenotypes associated with T2DM a …

Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

Proteases form one of the largest and more important groups of enzymes. They selectively
catalyze the hydrolysis of peptide bonds and can be divided into four major classes …

When caloric intake exceeds caloric expenditure, the positive caloric balance and storage of
energy in adipose tissue often causes adipocyte hypertrophy and visceral adipose tissue …

Expression of bone morphogenetic protein 4 (BMP4) in adipocytes of white adipose tissue
(WAT) produces “white adipocytes” with characteristics of brown fat and leads to a reduction …

Background: Exenatide, an incretin mimetic for adjunctive treatment of type 2 diabetes
(T2DM), reduced hemoglobin A1c (A1C) and weight in clinical trials. The objective of this …

Flavonoids have been identified as the antidiabetic components in a number of traditional
ethnic remedies. However, the mechanisms whereby these compounds exert their …

Obesity is a multifactorial disease characterized by an excessive weight for height due to an
enlarged fat deposition such as adipose tissue, which is attributed to a higher calorie intake …

Abstract Ethno Pharmacological Relevance: Traditional medicinal plants are practiced
worldwide for treatment of arthritis especially in developing countries where resources are …

Nondigestible fermentable dietary fibers such as oligofructose (OFS) exert an antidiabetic
effect and increase the secretion of glucagon-like peptide 1 (GLP-1). To determine the …