Role of zinc homeostasis in the pathogenesis of diabetes and obesity
A Fukunaka, Y Fujitani - International journal of molecular sciences, 2018 - mdpi.com
Zinc deficiency is a risk factor for obesity and diabetes. However, until recently, the
underlying molecular mechanisms remained unclear. The breakthrough discovery that the …
underlying molecular mechanisms remained unclear. The breakthrough discovery that the …
Properties and applications of flavonoid metal complexes
MM Kasprzak, A Erxleben, J Ochocki - Rsc Advances, 2015 - pubs.rsc.org
Flavonoids are widely occurring polyphenol compounds of plant origin with multiple
biological and chemical activities. Due to the presence of carbonyl and hydroxyl groups they …
biological and chemical activities. Due to the presence of carbonyl and hydroxyl groups they …
[HTML][HTML] The enormity of the zinc deficiency problem and available solutions; an overview
The societal cost of micronutrient deficiency (MND) or the “hidden hunger” is in millions of
dollars/year, reducing the GDP of some countries by as much as 11%. Zn is an important …
dollars/year, reducing the GDP of some countries by as much as 11%. Zn is an important …
Mammalian zinc transporters: nutritional and physiologic regulation
LA Lichten, RJ Cousins - Annual review of nutrition, 2009 - annualreviews.org
Research advances defining how zinc is transported into and out of cells and organelles
have increased exponentially within the past five years. Research has progressed through …
have increased exponentially within the past five years. Research has progressed through …
Neurobiology of zinc and zinc-containing neurons
CJ Frederickson - International review of neurobiology, 1989 - Elsevier
Publisher Summary This chapter discusses separate pools of CNS zinc, which are, vesicular
zinc, free zinc, and protein-bound zinc. Vesicular zinc is the one which is sequestered in the …
zinc, free zinc, and protein-bound zinc. Vesicular zinc is the one which is sequestered in the …
The role of assembly in insulin's biosynthesis
G Dodson, D Steiner - Current opinion in structural biology, 1998 - Elsevier
Insulin is synthesised as a single-chain precursor, preproinsulin, that contains an N-terminal
signal sequence and a connecting peptide linking the A and B chains of the insulin …
signal sequence and a connecting peptide linking the A and B chains of the insulin …
Zinc and insulin in pancreatic beta-cells
YV Li - Endocrine, 2014 - Springer
Abstract Zinc (Zn 2+) is an essential element crucial for growth and development, and also
plays a role in cell signaling for cellular processes like cell division and apoptosis. In the …
plays a role in cell signaling for cellular processes like cell division and apoptosis. In the …
Zinc and brain injury
DW Choi, JY Koh - Annual review of neuroscience, 1998 - annualreviews.org
▪ Abstract Zinc is an essential catalytic or structural element of many proteins, and a
signaling messenger that is released by neural activity at many central excitatory synapses …
signaling messenger that is released by neural activity at many central excitatory synapses …
Identification and cloning of a β-cell–specific zinc transporter, ZnT-8, localized into insulin secretory granules
F Chimienti, S Devergnas, A Favier, M Seve - Diabetes, 2004 - Am Diabetes Assoc
SLC30A8, a novel member of the zinc transporter (ZnT) family, was identified by searching
the human genomic and expressed sequence tag (EST) databases with the amino acid …
the human genomic and expressed sequence tag (EST) databases with the amino acid …
Solute carrier transporters as potential targets for the treatment of metabolic disease
T Schumann, J König, C Henke, DM Willmes… - Pharmacological …, 2020 - ASPET
The solute carrier (SLC) superfamily comprises more than 400 transport proteins mediating
the influx and efflux of substances such as ions, nucleotides, and sugars across biological …
the influx and efflux of substances such as ions, nucleotides, and sugars across biological …