The ability to rescue the activity of antimicrobials that are no longer effective against
bacterial pathogens such as Pseudomonas aeruginosa is an attractive strategy to combat …

Antibiotic resistance is one of the most pressing health issues of our days. It can arise due to
a multiplicity of factors, such as target modification, decrease in the drug uptake, changes in …

Acriflavine resistance protein B (AcrB) serves as prototype for multidrug resistance (MDR)
efflux transporters of resistance nodulation division (RND) superfamily. AcrB has been …

Highlights•Efflux pumps are membrane proteins involved in the transport of antimicrobial
drugs.•Inhibition of efflux systems can prevent drug resistance.•Strategies to avoid …

The resistance-nodulation-cell division transporter AcrB is responsible for energy
transduction and substrate recognition in the tripartite AcrAB-TolC efflux system in …

Overexpression of NorA efflux pumps plays a pivotal role in the multidrug-resistance
mechanism in S. aureus. Here, we investigated the activities of prenylated isoflavonoids …

Multidrug–resistant Escherichia coli is a continuously growing worldwide public health
problem, in which the well-known AcrAB-TolC tripartite RND efflux pump is a critical driver …

The increasing finding of pathogens and antibiotic resistance genes (ARGs) in drinking
water has become one of the most challenging global health threats worldwide. However …

The genus Methylobacterium tolerates hygiene agents like benzalkonium chloride (BAC),
and infection with this organism is an important public health issue. Here, we found that the …

Aliarcobacter butzleri is an emergent enteropathogen that can be found in a range of
environments. This bacterium presents a vast repertoire of efflux pumps, such as the ones …