[HTML][HTML] Molecular hydrogen enhances proliferation of cancer cells that exhibit potent mitochondrial unfolded protein response

T Hasegawa, M Ito, S Hasegawa, M Teranishi… - International Journal of …, 2022 - mdpi.com
Molecular hydrogen ameliorates pathological states in a variety of human diseases, animal
models, and cell models, but the effects of hydrogen on cancer have been rarely reported. In …

Bridging hydride at reduced H-cluster species in [FeFe]-hydrogenases revealed by infrared spectroscopy, isotope editing, and quantum chemistry

S Mebs, M Senger, J Duan, F Wittkamp… - Journal of the …, 2017 - ACS Publications
[FeFe]-Hydrogenases contain a H2-converting cofactor (H-cluster) in which a canonical [4Fe–
4S] cluster is linked to a unique diiron site with three carbon monoxide (CO) and two cyanide …

Acclimation of green algae to sulfur deficiency: underlying mechanisms and application for hydrogen production

TK Antal, TE Krendeleva, AB Rubin - Applied microbiology and …, 2011 - Springer
Hydrogen is definitely one of the most acceptable fuels in the future. Some photosynthetic
microorganisms, such as green algae and cyanobacteria, can produce hydrogen gas from …

How [FeFe]-hydrogenase facilitates bidirectional proton transfer

M Senger, V Eichmann, K Laun, J Duan… - Journal of the …, 2019 - ACS Publications
Hydrogenases are metalloenzymes that catalyze the conversion of protons and molecular
hydrogen, H2.[FeFe]-hydrogenases show particularly high rates of hydrogen turnover and …

A personal account on 25 years of scientific literature on [FeFe]-hydrogenase

JW Sidabras, ST Stripp - JBIC Journal of Biological Inorganic Chemistry, 2023 - Springer
Abstract [FeFe]-hydrogenases are gas-processing metalloenzymes that catalyze H2
oxidation and proton reduction (H2 release) in microorganisms. Their high turnover …

COPPER RESPONSE REGULATOR1–Dependent and –Independent Responses of the Chlamydomonas reinhardtii Transcriptome to Dark Anoxia

A Hemschemeier, D Casero, B Liu, C Benning… - The Plant …, 2013 - academic.oup.com
Anaerobiosis is a stress condition for aerobic organisms and requires extensive acclimation
responses. We used RNA-Seq for a whole-genome view of the acclimation of …

[HTML][HTML] Hydrogen and oxygen trapping at the H-cluster of [FeFe]-hydrogenase revealed by site-selective spectroscopy and QM/MM calculations

S Mebs, R Kositzki, J Duan, L Kertess, M Senger… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Abstract [FeFe]-hydrogenases are superior hydrogen conversion catalysts. They bind a
cofactor (H-cluster) comprising a four-iron and a diiron unit with three carbon monoxide (CO) …

Covalent attachment of FeFe hydrogenases to carbon electrodes for direct electron transfer

C Baffert, K Sybirna, P Ezanno, T Lautier… - Analytical …, 2012 - ACS Publications
Direct electron transfer between enzymes and electrodes is now commonly achieved, but
obtaining protein films that are very stable may be challenging. This is particularly crucial in …

Genetically engineered hydrogenases promote biophotocatalysis-mediated H2 production in the green alga Chlorella sp. DT

DW Yang, JW Syn, CH Hsieh, CC Huang… - International Journal of …, 2019 - Elsevier
Green algal hydrogenase (HydA) can produce hydrogen (H 2) biophotocatalytically.
Nevertheless, HydA is easily inhibited via its gas tunnel by O 2, which is a byproduct of …

Biosynthesis of complex iron–sulfur enzymes

EM Shepard, ES Boyd, JB Broderick… - Current opinion in chemical …, 2011 - Elsevier
Recent advances in our understanding of the mechanisms for the biosynthesis of the
complex iron–sulfur (Fe–S) containing prosthetic groups associated with [FeFe] …