Thymoquinone, as a novel therapeutic candidate of cancers
To date, natural products are widely used as pharmaceutical agents for many human
diseases and cancers. One of the most popular natural products that have been studied for …
diseases and cancers. One of the most popular natural products that have been studied for …
Thymoquinone, an active compound of Nigella sativa: role in prevention and treatment of cancer
Background: Cancer is the leading cause of death worldwide and the current mode of
cancer treatment causes side effects on normal cells and are still the key challenges in its' …
cancer treatment causes side effects on normal cells and are still the key challenges in its' …
Thymoquinone radiosensitizes human colorectal cancer cells in 2D and 3D culture models
S Al Bitar, F Ballout, A Monzer, M Kanso, N Saheb… - Cancers, 2022 - mdpi.com
Simple Summary Radiotherapy is a standard of care therapy that kills cancer cells but has
limited efficacy in targeting the resistant cancer stem cells (CSCs). The use of …
limited efficacy in targeting the resistant cancer stem cells (CSCs). The use of …
Plant-derived terpenoids: a promising tool in the fight against melanoma
P Kłos, D Chlubek - Cancers, 2022 - mdpi.com
Simple Summary Despite the numerous therapies, melanoma remains the deadliest of all
skin cancers; however, plant-derived terpenoids are defense molecules that have proven …
skin cancers; however, plant-derived terpenoids are defense molecules that have proven …
[HTML][HTML] Therapeutic potential of thymoquinone in combination therapy against cancer and cancer stem cells
Z Fatfat, M Fatfat, H Gali-Muhtasib - World journal of clinical …, 2021 - ncbi.nlm.nih.gov
The long-term success of standard anticancer monotherapeutic strategies has been
hampered by intolerable side effects, resistance to treatment and cancer relapse. These …
hampered by intolerable side effects, resistance to treatment and cancer relapse. These …
Recent findings on thymoquinone and its applications as a nanocarrier for the treatment of cancer and rheumatoid arthritis
Cancer causes a considerable amount of mortality in the world, while arthritis is an
immunological dysregulation with multifactorial pathogenesis including genetic and …
immunological dysregulation with multifactorial pathogenesis including genetic and …
Thymoquinone induces apoptosis of human epidermoid carcinoma A431 cells through ROS-mediated suppression of STAT3
JE Park, DH Kim, E Ha, SM Choi, JS Choi… - Chemico-biological …, 2019 - Elsevier
Black seed (Nigella sativa) oil has been used in various dermatological applications, and its
major constituent, thymoquinone (TQ) has been shown to exhibit antiproliferative activity …
major constituent, thymoquinone (TQ) has been shown to exhibit antiproliferative activity …
[HTML][HTML] Radiotherapy in preclinical models of brain metastases: a review and recommendations for future studies
W Shi, G Tanzhu, L Chen, J Ning, H Wang… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Brain metastases (BMs) frequently occur in primary tumors such as lung cancer, breast
cancer, and melanoma, and are associated with notably short natural survival. In addition to …
cancer, and melanoma, and are associated with notably short natural survival. In addition to …
Response of skin-derived and metastatic human malignant melanoma cell lines to thymoquinone and thymoquinone-loaded liposomes
P Kłos, M Perużyńska, M Baśkiewicz-Hałasa… - Pharmaceutics, 2022 - mdpi.com
Thymoquinone has been proved to be effective against neoplasms, including skin cancer. Its
high lipophilicity, however, may limit its potential use as a drug. Melanoma remains the …
high lipophilicity, however, may limit its potential use as a drug. Melanoma remains the …
Anticancer and anti-metastatic role of thymoquinone: Regulation of oncogenic signaling cascades by thymoquinone
Cancer is a life-threatening and multifaceted disease. Pioneering research works in the past
three decades have mechanistically disentangled intertwined signaling networks which play …
three decades have mechanistically disentangled intertwined signaling networks which play …