Infusion reactions (IRs) create a translational hurdle for many novel therapeutics, including
those utilizing nanotechnology. Nucleic acid nanoparticles (NANPs) are a novel class of …

In biological systems, large and complex structures are often assembled from multiple
simpler identical subunits. This strategy—homooligomerization—allows efficient genetic …

Abstract The International Society of RNA Nanotechnology and Nanomedicine (ISRNN)
serves to further the development of a wide variety of functional nucleic acids and other …

Cisplatin (cis-diaminedichloroplatinum (II), CDDP) plays a crucial role in the treatment of
various malignant tumors. However, its clinical efficacy and applicability are restricted by …

Nucleic acids are programmable and biocompatible polymers that have beneficial uses in
nanotechnology with broad applications in biosensing and therapeutics. In some cases …

The relatively straightforward methods of designing and assembling various functional
nucleic acids into nanoparticles offer advantages for applications in diverse diagnostic and …

The precise regulation of interactions of specific immunological components is crucial for
controllable immunomodulation, yet it remains a great challenge. With the assistance of …

Left ventricular hypertrophy and fibrosis are major risk factors for heart failure, which require
timely and effective treatment. Genetic therapy has been shown to ameliorate hypertrophic …

Recent advances in nanotechnology now allow for the methodical implementation of
therapeutic nucleic acids (TNAs) into modular nucleic acid nanoparticles (NANPs) with …

Multifunctional hybrid nanoparticles are being developed to carry a wide variety of
therapeutic and imaging agents for multiple biomedical applications. Polysilsesquioxane …